Which one of the following statements about arene oxides is FALSE? O The NIH shift is what makes arene oxides carcinogenic. O Ring opening of an arene oxide can afford an addition product and/or a rearranged product. O Large polycyclic aromatic hydrocarbons such as benzo[a]pyrene are especially susceptible to arene oxide formation. O The NIH shift mechanism was discovered at the National Institutes of Health. O Cytochrome P450 is the powerful biological oxidant that epoxides an arene to give an arene oxide.

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter19: Aldehydes And Ketones: Nucleophilic Addition Reactions
Section19.SE: Something Extra
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Which one of the following statements about arene oxides is FALSE?
O The NIH shift is what makes arene oxides carcinogenic.
O Ring opening of an arene oxide can afford an addition product and/or a rearranged
product.
O Large polycyclic aromatic hydrocarbons such as benzo[a]pyrene are especially
susceptible to arene oxide formation.
The NIH shift mechanism was discovered at the National Institutes of Health.
O Cytochrome P450 is the powerful biological oxidant that epoxides an arene to give
an arene oxide.
Transcribed Image Text:Which one of the following statements about arene oxides is FALSE? O The NIH shift is what makes arene oxides carcinogenic. O Ring opening of an arene oxide can afford an addition product and/or a rearranged product. O Large polycyclic aromatic hydrocarbons such as benzo[a]pyrene are especially susceptible to arene oxide formation. The NIH shift mechanism was discovered at the National Institutes of Health. O Cytochrome P450 is the powerful biological oxidant that epoxides an arene to give an arene oxide.
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