Which of the following treatments is appropriate for a patient with diffuse toxic goiter during the third trimester of pregnancy?A. Subtotal thyroid gland resectionB. Treatment with radioactive iodineC. Lugol's solutionD. PropylthiouracilE. Prednisolone
Which of the following treatments is appropriate for a patient with diffuse toxic goiter during the third trimester of pregnancy?
A. Subtotal thyroid gland resection
B. Treatment with radioactive iodine
C. Lugol's solution
D. Propylthiouracil
E. Prednisolone
INTRODUCTION:
Diffuse goiter during the third semester of the pregnancy results in the rare disorder known as maternal hyperthyroidism.
Grave’s disease is a condition in which there occurs diffuse toxic goiter, which is characterized by the production of autoantibodies which activates the TSH receptor. These autoantibodies cross the placenta and can cause fetal and neonatal thyroid dysfunctioning
Most discriminating features of hyperthyroidism in pregnancy are-
tremors, tachychardia, weight loss, murmur, lid lag and exophthalmos.
Treatment :
Antithyroid antibodies are commonly prescribed to the patients suffering from the disease.
Normally, radioiodine is contradicted in this condition and surgery also requires pretreatment with drugs. So, the first line of treatment is the thioamide drug therapy. So far, This is the best treatment.
These drugs include propylthiouracil, methimazole, carbimazole etc.
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