Which of the following statements is true? Question 9 options: a) Executioner caspases are activated by cleavage. b) Initiator caspases are activated by cleavage. c) Executioner caspases are activated by dimerization. d) Executioner caspases trigger apoptosis but initiator caspases does not.
Which of the following statements is true?
Question 9 options:
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Executioner caspases are a group of caspases that are responsible for the dismantling of the cell during apoptosis. They are activated by cleavage by initiator caspases. Once activated, executioner caspases cleave a variety of cellular proteins, including cytoskeletal proteins, nuclear proteins, and DNA repair proteins. This leads to the characteristic morphological changes of apoptosis, such as cell shrinkage, nuclear condensation, and DNA fragmentation.
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