Which of the following statements about "Focused transcription initiation", "Dispersed transcription initiation" and "transcription start sites" (TSS) are correct. Note: it's more than 1! The majority of human genes is regulated from dispersed promoters. O Focused initiation starts form a single or narrow set of transcription start sites (TSSS). Focused and dispersed transcription initiation refer to the extreme ends of a continuum of initiation patterns. Dispersed transcription initiation is the evolutionary more ancient mechanism. RNA-seq is the preferred method to map TSS.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Which of the following statements
about "Focused transcription
initiation", "Dispersed transcription
initiation" and "transcription start sites"
(TSS) are correct.
Note: it's more than 1!
The majority of human genes is
regulated from dispersed promoters.
Focused initiation starts form a single or
narrow set of transcription start sites
(TSSS).
Focused and dispersed transcription
initiation refer to the extreme ends of a
continuum of initiation patterns.
Dispersed transcription initiation is the
evolutionary more ancient mechanism.
RNA-seq is the preferred method to
map TSS.
Transcribed Image Text:Which of the following statements about "Focused transcription initiation", "Dispersed transcription initiation" and "transcription start sites" (TSS) are correct. Note: it's more than 1! The majority of human genes is regulated from dispersed promoters. Focused initiation starts form a single or narrow set of transcription start sites (TSSS). Focused and dispersed transcription initiation refer to the extreme ends of a continuum of initiation patterns. Dispersed transcription initiation is the evolutionary more ancient mechanism. RNA-seq is the preferred method to map TSS.
Why do chromatin remodeling factors
exist?
Remodeling factors are not essential but
help regulate gene expression.
Nucleosomes are intrinsically immobile
on a biological timescale at
physiological conditions.
Remodeling factors are essential
regulators of gene expression through
covalent modification of histone tails.
Transcribed Image Text:Why do chromatin remodeling factors exist? Remodeling factors are not essential but help regulate gene expression. Nucleosomes are intrinsically immobile on a biological timescale at physiological conditions. Remodeling factors are essential regulators of gene expression through covalent modification of histone tails.
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