new type of antibiotic targeting prokaryotic transcription prevents RNA polymerase from binding to its promoters. Which of the following provides a likely mechanism for transcription inhibition through these antibiotics? Group of answer choices The antibiotics prevent unwinding of DNA. The antibiotics block RNA exit from the RNA polymerase The antibiotics prevent the removal of sigma factor from the polymerase The antibiotics promote premature rho-mediated termination of transcription. The antibiotics prevent RNA polymerase binding to sigma factor

new type of antibiotic targeting prokaryotic transcription prevents RNA polymerase from binding to its promoters. Which of the following provides a likely mechanism for transcription inhibition through these antibiotics? Group of answer choices The antibiotics prevent unwinding of DNA. The antibiotics block RNA exit from the RNA polymerase The antibiotics prevent the removal of sigma factor from the polymerase The antibiotics promote premature rho-mediated termination of transcription. The antibiotics prevent RNA polymerase binding to sigma factor

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Description: A new type of antibiotic targeting prokaryotic transcription prevents RNA polymerase from binding to its promoters. Which of the following provides a likely mechanism for transcription inhibition through these antibiotics?Group of answer choicesThe a

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter14: Gene Regulation

Section: Chapter Questions

Problem 9TYU: A mutation that inactivates the repressor gene of the lac operon results in (a) the continuous...

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A particular mutation in the bacterial sigma factor allows this protein to bind RNA polymerase but prevents it from coming off (detaching) RNA polymerase once it binds. What specific effect will this mutation have on transcription? It will prevent the transcription termination exerted by the Rho protein. It will prevent the formation of closed complexes between RNA polymerase and the promoter. It will prevent the formation of open complexes between RNA polymerase and the promoter. It will prevent the transition from the transcription initiation to the transcription elongation stage. It will prevent the synthesis of abortive RNA transcripts while the RNA polymerase is bound at the promoter.
A cell that has a mutation that increases the catalytic rate of RNA Polymerase II will likely have which of the following effects: shift the start of transcription downstream Have no effect Cause start site shifts in both directions shift the start of transcription upstream
Choose the effect of the given agents to translation or transcription. Choices: RNA polymerase inhibition RNA polymerase II inhibition prevention of ribosomal movement in prokaryotes disruption of elongation stage of translation disruption of initiation stage of translation prevention of ribosomal movement in eukaryotes 1. Rifampicin 2. Diptheria Toxin 3. Puromycin 4. Amanitin 5. Tetracycline
Which of the following characterize RNA polymerase Il transcriptional termination in eukaryotes? Endonuclease cleavage of the RNA transcript and 5' to 3' exonuclease activity a protein known as Ratl None of the provided answers, transcriptional termination occurs in prokaryotes. Recognition of the transcriptional stop codon by a release factor. Hairpin structure formation on the newly synthesized RNA molecule which disrupts the DNA-RNA hybrid at a poly-U RNA sequence Binding of the Rho protein.
Listed below are steps in the transcription process. Reorganize the list so the steps in the correct order- starting with the first step in initiating transcription and ending with completion of a new strand of RNA (in other words- from start to finish of transcription). RNA polymerase reaches the termination signal DNA unwinds underneath RNA polymerase at transcription start site RNA polymerase is recruited to the promoter region mRNA transcript is released General Transcription factors bind TATA box (and other DNA sequences) in the promoter region General Transcription Factors unbind from promoter region mRNA transcript synthesis occurs RNA polymerase moves along the template strand in the 3’ to 5’ direction
A mutation that inactivates the repressor gene of the lac operon results in (a) the continuous transcription of the structural genes (b) no transcription of the structural genes (c) the binding of the repressor to the operator (d) no production of RNA polymerase (e) no difference in the rate of transcription
The sigma factor protein's role in transcription in E. coli includes which of the following? None of the answer options are correct. plays a role in transcription termination forms part of the core enzyme required for transcription initiation helps the siRNA to bind to the promoter All of the answer options are correct. contributes to the proof-reading activity of RNA polymerase And The role of tRNA is to serve as an intermediate in the decoding of genes. serve as general translational components of the ribosome. facilitate protein trafficking in protein secretion. facilitate splicing of pre-messenger RNAs. act as vehicles bringing amino acids to the site of protein synthesis. None of the answer choices are correct.
Initiation of prokaryotic transcription is primarily regulated by: Question 1 options: Core enzyme of RNA Polymerase Chromatin structure Activators Repressors Sigma factors
A researcher discovered Suramin as a potent and selective inhibitor of Mycobacterium tuberculosis RecA protein and the SOS response. What would be the outcome if the action of RecA was inhibited during the SOS response? O LexA would not autolyse, and therefore the transcription of DNA repair genes would not occur; the bacteria would likely not survive. O LexA would autolyse, and therefore the transcription of repair genes would not occur; that would be lethal to the bacteria. LexA would autolyse, and therefore the transcription of DNA repair genes would occur; and the bacteria will be susceptible to antibiotics. LexA would not autolyse, and therefore the transcription of repair genes would occur; essentially that would be lethal to the bacteria.
Consider this list (below) of steps involved in transcription. These steps are out of order. TRANSCRIPTION: 1. mRNA travels through a nuclear pore and enters the cytoplasm 2. the mRNA polymerase attaches at the start of a specific gene 3. RNA polymerase reads the gene surface4. a transcription factor bonds to a promoter site5. DNA molecule is unwound 6. a complimentary mRNA is produced What is the correct order of this transcription?
The following segment of DNA is part of the RNA-coding sequence of a transcription unit. If the bottom strand is template, which of the following RNA sequences would be transcribed? DNA: 5-'ATAGGCGATGCCA-3' 3'-TATCCGCTACGGT-5' O 5'-UAUCCGCUACGGU-3' O 5'-ACCGUAGCGGAUA-3' O 5'-AUAGGCGAUGCCA-3' O 5'-UGGCAUCGCCUAU-3'
In bacteria sigma factors: 1. Transcript factors2. Specialized subunit of the core enzyme 3. Signal termination 4. Guide RNA polymerase to different kinds of promoters