Which of the following most likely has a sequence of hydrophobic amino acids that permits the protein to be embedded in membranes? Select one: a. translocator (TIM/TOM) b. none of the above c. signal peptidase d. chaperone (HSP) e. ubiquitin
Proteins
We generally tend to think of proteins only from a dietary lens, as a component of what we eat. However, they are among the most important and abundant organic macromolecules in the human body, with diverse structures and functions. Every cell contains thousands and thousands of proteins, each with specific functions. Some help in the formation of cellular membrane or walls, some help the cell to move, others act as messages or signals and flow seamlessly from one cell to another, carrying information.
Protein Expression
The method by which living organisms synthesize proteins and further modify and regulate them is called protein expression. Protein expression plays a significant role in several types of research and is highly utilized in molecular biology, biochemistry, and protein research laboratories.
Correct answer: (a) Translocator (TIM/TOM)
- The transport of proteins inside the mitochondrial membrane is mediated by a special protein complex called as the TIM TOM complex or TIM TOM translocator.
- These translocators are embedded inside the mitochondrial matrix and along with other components allow the transport of specific proteins that have a specific signal sequence to be translocated inside the membrane.
- Therefore translocators have a sequence of hydrophobic amino acids that permits the protein to be embedded in membranes.
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