Which of the following compounds can produce a B-lactone (beta-lactone) upon intramolecular esterification? B) 3-hydroxymethanoic acid E) 3-hydroxy-3-methylpentanoic acid A) 2-hydroxybutanone D) 4-hydroxypentanoic acid C) 2-hydroxyoctanonoic acid F) 5-hydroxyheptanoic acid

Which of the following compounds can produce a B-lactone (beta-lactone) upon intramolecular esterification? B) 3-hydroxymethanoic acid E) 3-hydroxy-3-methylpentanoic acid A) 2-hydroxybutanone D) 4-hydroxypentanoic acid C) 2-hydroxyoctanonoic acid F) 5-hydroxyheptanoic acid

Introduction to General, Organic and Biochemistry

11th Edition

ISBN:9781285869759

Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Chapter16: Amines

Section: Chapter Questions

Problem 16.34P

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Question

14.) Which of the following compounds can produce a B-lactone (beta-lactone) upon intramolecular esterification?
B) 3-hydroxymethanoic acid
E) 3-hydroxy-3-methylpentanoic acid
A) 2-hydroxybutanone
D) 4-hydroxypentanoic acid
C) 2-hydroxyoctanonoic acid
F) 5-hydroxyheptanoic acid

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What products are formed when all of the amide and ester bonds are hydrolyzed in each of the following compounds? Tamiflu [part (a)] is the trade name of the antiviral agent oseltamivir, thought to be the most effective agent in treating influenza. Aspartame [part (b)] is the artificial sweetener used in Equal and many diet beverages. One of the products of this hydrolysis reaction is the amino acid phenylalanine. Infants afflicted with phenylketonuria cannot metabolize this amino acid, so it accumulates, causing mental retardation. When the affliction is identified early, a diet limiting the consumption of phenylalanine (and compounds like aspartame that are converted to it) can make a normal life possible.