Which mutation could result in the removal of a site for glycosylation or phosphorylation?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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First letter
U
U
UUU Phenyl-
UUC alanine
Leucine
UUA
UUG
CUU
CUC
CUA
CUG
AUU
AUC Isoleucine
A AUA
AUG
GUU
GUC
Leucine
GUA
GUG
Methionine;
start codon
Valine
Normal, wild-type sequence
A. mutation I
mutation A
UCU
UCC
mutation C
UCA
UCG
mutation B
CCU
CCC
CCA
CCG
ACU
ACC
ACA
ACG
GCU
GCC
B. mutation II
C. mutation III
Point mutations are underlined.
GCA
GCG
C
Second letter
Serine
Proline
Threonine
Alanine
UAU
UAC
Tyrosine
UAA Stop codon
UAG Stop codon
CAU
CAC
A
CAA
CAG
Histidine
Glutamine
AAU
AAC Asparagine
AAA
AAG Lysine
GAU Aspartic
GAC acid
GAA Glutamic
GAG
acid
G
UGU
UGC Cysteine
UGA Stop codon A
UGG Tryptophan G
CGU
CGC
CGA
CGG
AGU
AGC
GGU
GGC
AGA
AGG Arginine
GGA
GGG
AUG UCU CGG GCU UAC
AUA UCU CGG GCU UAC
AUG UUU CGG GCU UAC
AUG UCU AGG GCU UAC
Arginine
Serine
Glycine
Which mutation could result in the removal of a site for
glycosylation or phosphorylation?
DOAGUO AGUO AGUAG
Third letter
с
Transcribed Image Text:First letter U U UUU Phenyl- UUC alanine Leucine UUA UUG CUU CUC CUA CUG AUU AUC Isoleucine A AUA AUG GUU GUC Leucine GUA GUG Methionine; start codon Valine Normal, wild-type sequence A. mutation I mutation A UCU UCC mutation C UCA UCG mutation B CCU CCC CCA CCG ACU ACC ACA ACG GCU GCC B. mutation II C. mutation III Point mutations are underlined. GCA GCG C Second letter Serine Proline Threonine Alanine UAU UAC Tyrosine UAA Stop codon UAG Stop codon CAU CAC A CAA CAG Histidine Glutamine AAU AAC Asparagine AAA AAG Lysine GAU Aspartic GAC acid GAA Glutamic GAG acid G UGU UGC Cysteine UGA Stop codon A UGG Tryptophan G CGU CGC CGA CGG AGU AGC GGU GGC AGA AGG Arginine GGA GGG AUG UCU CGG GCU UAC AUA UCU CGG GCU UAC AUG UUU CGG GCU UAC AUG UCU AGG GCU UAC Arginine Serine Glycine Which mutation could result in the removal of a site for glycosylation or phosphorylation? DOAGUO AGUO AGUAG Third letter с
Expert Solution
Step 1: glycosylation and phosphorylation

glycosylation and phosphorylation are post tranlational processes. In glycosylation  sugars or carbohydrate molecules are added to the translated sequence of amino acids. usually two common aminoacids involved in glycosylation  are serine and threonine which possess hydroxyl ( OH ) groups that can serve as attachment sites for carbohydrate molecules.

in phosphorylation, phosphate group (Po4) is added to the translated aminoacid chain. the most suitable amino acids for phosphorylation are serine , threonine  and tyrosine 

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