When used as fuel, hexanoic acid provides more useable energy per gram than does glucose.  Both of these compounds contain 6 carbons.  Why is hexanoic acid more energy dense than glucose? Hexanoic acid is more highly reduced Energy needs to be used to linearize the cyclic glucose Glycolysis is inherently inefficient Fatty acids are processed through the CAC which extracts more e⁻ FA are broken down in the mitochondria while glucose is broken down in the cytosol

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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When used as fuel, hexanoic acid provides more useable energy per gram than does glucose.  Both of these compounds contain 6 carbons.  Why is hexanoic acid more energy dense than glucose?


Hexanoic acid is more highly reduced
Energy needs to be used to linearize the cyclic glucose
Glycolysis is inherently inefficient
Fatty acids are processed through the CAC which extracts more e⁻
FA are broken down in the mitochondria while glucose is broken down in the cytosol
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