What would cause our red blood cells to produce 2,3-diphosphoglycerate?    Select 2 correct answer(s)     Living at high altitudes   Cardiopulmonary disorders   Eating a burrito   Sedentary lifestyle

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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What would cause our red blood cells to produce 2,3-diphosphoglycerate? 

 
Select 2 correct answer(s)

 

 

Living at high altitudes

 

Cardiopulmonary disorders

 

Eating a burrito

 

Sedentary lifestyle

 

Expert Solution
Step 1

Erythrocyte 2,3-DPG helps haemoglobin oxygenation by binding to deoxyhemoglobin and facilitating oxygen transfer. In red blood cells, 2,3-diphosphoglycerate (2,3-DPG) levels rise in response to anaemia/hypoxia, causing a shift in the oxygen dissociation curve, allowing for more efficient oxygen delivery.

1. Living at a high altitude place

- Living at high altitude can simulate hypoxic conditions which can lead to rise in 2,3 DPG levels.

2. Cardiopulmonary Disorders 

- being affected with such disorders can lead to less efficient oxygen delivery again producing hypoxic conditions. It can also make 2,3 DPG levels rise.

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