What would be the best base to use toconduct a Claisen Condensation reactionwith the following ester?Sodium PropoxideSodium HydroxideSodium EthoxideSodium Methoxide

In Claisen condensation, strong bases such as hydroxides are not used due to the possibility of…

Answered: What would be the best base to use to…

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter23: Amines

Section: Chapter Questions

Problem 23.29P

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Similar questions

Draw structures for the carbonyl electrophile and enolate nucleophile.
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The product of reaction between formaldehyde with 2-methyl propanal give 2,2-dimethyl-3-hydroxy propanal 2,2-dimethyl-3-hydroxy propanone 2,2-dimethyl-3-hydroxy propanoic acid 2,2-dimethyl-3-hydroxy propanol 4-phenyl-3-buten-2-one prepared from reaction between Benzaldehyde with acetic acid Benzaldehyde with acetaldehyde Benzaldehyde with formaldehyde Benzaldehyde with acetone Which predict product for reaction between heptane-6-one-1-al with sodium hydroxide * 1-(2-hydroxycyclopentyl) pentanone 1-(2-hydroxycyclopentyl) butanone 1-(2-hydroxycyclopentyl) ethanone 1-(2-hydroxycyclopentyl) propanone
Draw the products obtained by reacting a sulfonitric mixture with: 4-nitrophenol, 2,4-dinitrophenol, phenol, 4-methoxyphenol, 4-chlorophenol.
In the following reaction mechanism, what best describes the role of the Grignard reagent? + CH₂MgBr 1) ether 2) H3O+ The Grignard reagent acts as a nucleophile and attacks the carbonyl carbon. The Grignard reagent acts as an electrophile and is attacked by the oxygen. The Grignard reagent is first protonated by the acid. The Grignard reagent acts as a nucleophile and removes a proton from the methyl group attached to the carbonyl carbon.
+ Choose the best reagents to complete the following reaction. HN a
What is the product resulted due to the reaction of 2-hydroxy-3-methoxybenzaldehyde with ethyl bromoacetate in a basic solution indicating all the reagents and intermediates occurred during the reaction? What is the product obtained when product A reacted with ethyl acetate in the same basic solution?
The following pKa values have been measured. Explain why a hydroxyl group in the para position decreases the acidity while a hydroxyl group in the meta position increases the acidity.
mixed Claisen condensation of methyl benzoate with methyl propanoate 1 gives * 3-ethyl-2-methyl-3-oxo-3-phenylpropanoate O ethyl-2-methyl-3-oxo-3-phenylpropanoate O Methyl-2-methyl-3-oxo-3-phenylpropanoate 3-Methyl-2-methyl-3-oxo-3-phenylpropanoate Micheal reaction of 2-methyl-1,3-cyclohexanedione with methylvinylketone 1 2-methyl-2-(3-oxobutyl)-1,3-cyclohexanedion 4-methyl-2-(3-oxobutyl)-1,3-cyclohexanedion 3-methyl-2-(3-oxobutyl)-1,3-cyclohexanedion
Lexan can also be prepared by the acid-catalyzed reaction of diphenyl carbonate with bisphenol A. Draw a stepwise mechanism for this process.
The Stork reaction is a condensation reaction between an enamine donor and an α,β-unsaturated carbonyl acceptor. The overall reaction consists of a three-step sequence of formation of an enamine from a ketone, Michael addition to an α,β-unsaturated carbonyl compound, and hydrolysis of the enamine in dilute acid to regenerate the ketone. Consider the Stork reaction between acetophenone and 3-buten-2-one. Draw the structure of the product of the enamine formed between acetophenone and pyrrolidine. Draw the structure of the Michael addition product. Draw the structure of the final product.
What products are formed in the base hydrolysis of the ester shown below with NaOH? Sodium ethanoate and ethanol B) Ethanol and ethanoic acid Ethanoic acid and sodium ethoxide Sodium ethanoate and water Methanol and sodium propanoate CH, C-O-CH2-CH,

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What would be the best base to use to conduct a Claisen Condensation reaction with the following ester? Sodium Propoxide Sodium Hydroxide Sodium Ethoxide Sodium Methoxide