What might be predicted to happen when the following substance undergoes Friedel-Crafts acylation? ON-O-CH₂-O B Substitution occurs in ring B, p- to the methylene group Substitution occurs in ring A, o- to the nitro group Substitution occurs in ring A, o- to the methylene group Substitution occurs in ring B, m- to the methylene group B C

What might be predicted to happen when the following substance undergoes Friedel-Crafts acylation? ON-O-CH₂-O B Substitution occurs in ring B, p- to the methylene group Substitution occurs in ring A, o- to the nitro group Substitution occurs in ring A, o- to the methylene group Substitution occurs in ring B, m- to the methylene group B C

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Related questions

Q: НО, ОН ОН ОН CO₂Et

A: To provide the synthetic route for the iven target molecules from the iven starting materials

Q: Which reaction will not give the indicated product? 1. CH, CHO 2. H₂O OH O CH₂CH₂OH, H* N H OH…

A: Check the options by the mechanism process.

Q: As shown below, pyridine -oxide G can undergo electrophilic aromatic substitution with electrophile…

Q: а. OH b. с. H3C CH3 HO HO

Q: L.CH,M B дет дета НО (CH₂)₂N Compound A (CH₂) N Tamoxifen

A: Given synthesis reaction of Tamoxifen.Tamoxifen is an estrogen receptor modulator that is used in…

Q: Predict products and propose mechanisms for the common electrophilic aromaticsubstitutions:…

A: Given reactions, Electrophilic aromatic substitution reactions. Halogenation, nitration,…

Q: Propose a synthesis for the following compound from benzene. Br

A: Given compound: We have to synthesize the above compound from benzene.

Q: Starting with benzene and using any other reagents of your choice, design a synthesis for the…

A: The question is based on the concept of organic synthesis. we need to synthesize the product using…

Q: Part III, Reaction Mechanisms 16. (15 pts) Show the mechanism for the following transformation. осно…

A: The hydrolysis of an ester in the presence of sodium hydroxide ( NaOH ) or hydrochloric acid ( H3O+…

Q: 14.53 Friedel-Crafts alkylation of benzene with 1-chlorobutane gave a product for which the 'H and…

A: The structure is as follows:

Q: nucleophilic

A: Dear student I have given answer to your question in the image format.

Q: Alpha-phellandrene, C10H16, is a pleasant-smelling chiral compound that may be obtained from the…

A: Phellandrene is a cyclic monoterpene, widely spread in nature. Phellandrene was isolated from…

Q: он OH OH он OCH3 CI CH3 10.0 10.2 9.2 7.7

A: Give an explanation, why the acidity of these phenolic derivatives give these pKa value?

Q: Butter yellow is a dye once used to color margarine. It has since been shown to be carcinogenic, and…

A: The synthesis of butter yellow is a multistep reaction. It is a diazo compound or derivative of…

Q: 1) LIAIH4 2) Н,о 14.

Q: 9. Starting from benzene and using any necessary reagents, synthesize the following compounds. CI…

A: These are simple questions of reagent and reaction mechanism of organic reaction.

Q: Provide the reagents for the synthesis: CH₂ ? a CH3 COOH

A: HCN adds to alkene to form alkyl cyanide through Markovnikov rule.Markovnikov rule: It states that…

Q: Nucleophilic aromatic substitution involves the formation of a resonance-stabilized carbanion…

Q: earn the term “oxime” and then look up a reaction called the “Beckmann rearrangement.” Why is this…

Question

What might be predicted to happen when the following substance
undergoes Friedel-Crafts acylation?
O₂N.
A
A
B
C
D
-CH₂-
B
Substitution occurs in ring B, p- to the methylene group
Substitution occurs in ring A, o- to the nitro group
Substitution occurs in ring A, o- to the methylene group
Substitution occurs in ring B, m- to the methylene group

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1: Describing activating and deactivation of benzene ring

VIEW

Step 2: Analysing the given question

VIEW

Solution

VIEW

Step by step

Solved in 3 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

Question 9 of 9 Choose the best set of conditions for a Friedel-Crafts acylation of aromatic compounds. A) CH;C(O)CI, AICI3 B) CH3C(O)CI C) CH;C(O)CI, NaCI D) CH3C(O)CI, Cl2, H2O
Use retrosynthetic analysis to show which reagents are necessary to carry out the following syntheses. a. b. d. NO2 O₂N OH Br NH2 CO₂H NH2
Provide the final product and mechanism for the following reactions
II. Alcohols in synthesis A. What are the strategies for the synthesis of alcohols by nucleophilic substitution reactions using halide leaving groups with hydroxide as a nucleophile? How do you predict possible by-products that could arise from this strategy? How do you use the less acetate nucleophile followed by treatment with NaOH to avoid by-products?
Alpha-phellandrene, C₁0H₁6, is a pleasant-smelling chiral compound that may be obtained from the leaves of eucalyptus trees. It has the molecular formula C₁0H16 and a UV absorption maximum at 263 nm. On hydrogenation with a palladium catalyst, an achiral hydrocarbon with the formula C₁0H20 is obtained. Ozonolysis of alpha-phellandrene, followed by treatment with zinc and acetic acid, produces the following two compounds: 0 || CH3C-CH 0 || ● Propose a structure for alpha-phellandrene. (+ || HCCH₂CHCH I CH(CH3)2 • You do not have to consider stereochemistry. You do not have to explicitly draw H atoms. • In cases where there is more than one answer, just draw one. n [ ]# ?
Name and Draw the structures of all possible chemical (Electrophilic aromatic substitution) reactions of the compound namely; Halogenation (Chlorination or Bromination) Nitration Sulphonation Friedal Craft Alkylation Friedal Craft Acylation
20:33 1 : ●●● all the proper notations for depicting resonance. 4. Provide the full mechanism (curved arrows and intermediates) that leads to the product in the scheme below. Draw the structure of the product to help you see how the starting materials will combine. Use that as a clue to figure out how to draw the mechanism arrows. ccare in your scheme. Be sure to use NaOEt 00 i 5. Provide the major organic product of the reaction shown. Determine if these conditions are best for SN2, SN1, E2, or E1. Be sure to indicate stereochemistry by using the proper wedges/dashes in the product. acetone phenyl butanoate Send a chat O
Why does cyclohexanol have a pK, of 18 and phenol, despite its similarities in structure, have a pK, of 10? Phenol has a resonance-stabilized conjugate base, which increases the stability of the base and favors its formation Cycohexanol has a resonance-stabilized structure, which increases its stability and reduces the likelihood that it will react to form a conjugate base Phenol has a resonance-stabilized conjugate base, which decreases the stability of the base and inhibits its formation Cycohexanol has a resonance-stabilized conjugate base, which increases the stability of the base and favors its formation Phenol has a resonance-stabilized conjugate base, which decreases the stability of the base and favors its formation
Spirocyclic compounds, such as compound 3, are made and used by insects for the purposes of communication. The first step of a synthesis of compound 3 involves treatment of (S)-1,2-epoxypropane (compound 1) with lithium acetylide, followed by acid workup, to give compound 2, as shown below (J. Org. Chem. 2005, 70, 3054-3065). Identify the structure of compound 2 and provide a mechanism for its formation. (Hint: The carbon-lithium bond reacts in a way that is similar to the carbon-magnesium bond of a Grignard reagent.) 1 13.17 a 1) Li—= 2) H₂O+ нас!!!!!! C5H8O Edit Drawing 2 Ž Modify the given structure of the starting material to draw the major product. an 3