Nucleophilic aromatic substitution involves the formation of a resonance-stabilized carbanion intermediate called a Meisenheimer complex as the nucleophile attacks the ring carbon carrying the eventual leaving group; electron-withdrawing groups ortho and/or para to the site of attack help to stabilize this structure via resonance. For the reaction below, draw the structure of the stabilized reaction intermediate in the box below. CI F3C CF3 NO₂ F3C N CF3 NO₂ • You do not have to consider stereochemistry. • Draw the Meisenheimer complex with a formal charge of 0 on the nucleophilic atom. If more than one resonance structure is possible, only draw the most important one.

Nucleophilic aromatic substitution involves the formation of a resonance-stabilized carbanion intermediate called a Meisenheimer complex as the nucleophile attacks the ring carbon carrying the eventual leaving group; electron-withdrawing groups ortho and/or para to the site of attack help to stabilize this structure via resonance. For the reaction below, draw the structure of the stabilized reaction intermediate in the box below. CI F3C CF3 NO₂ F3C N CF3 NO₂ • You do not have to consider stereochemistry. • Draw the Meisenheimer complex with a formal charge of 0 on the nucleophilic atom. If more than one resonance structure is possible, only draw the most important one.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

Match the reactant with the product of its reaction with HClO4. Leave blank if there is no reaction. Group of answer choices K2S KHCO3 HNO3 K2SO3
Draw the structure of an alkene with one double bond that would give the following compound as the only product after ozonolysis followed by H2O2.
Which of the following is the product in this Grignard reaction? ОН O 1) O 2) ОН 4) H.
For each of the following reactions predict the major product(s). LOCH3 CI AICI3 HNO3 NH2 1. NaNO2, HCI 2. HBF4, A
Fill in the reagents below/above the arrow in the ff reaction
Draw the reactant of the following intramolecular Claisen condensation
#16h. Provide the missing reactants, reagents, or products for the following reaction sequences below.
9. Choose the major organic product of the reaction. A В C II IV Br Br Br Br Br Br2 Br Br 0°C Br IV
None
6) Provide the major organic product for the reaction below Br NBS, CCl4 heat, A -Br B Br Br Br con x D
Please don't provide handwritten solution
Consider the reaction scheme below. (i) H3COCHN CO₂Et A H₂N OH EtO OEt B C6H₁1 NO2 base Ha Identify the reagent(s) and conditions A and the intermediate B in this reaction scheme.