What is the rationale for developing anti-cancer agents that inhibit telomerase?

Answered: What is the rationale for developing…

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter12: Genes And Cancer

Section: Chapter Questions

Problem 9QP: What is the difference between a proto-oncogene and a tumor-suppressor gene?

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What is the rationale for developing anti-cancer agents that inhibit telomerase?

Expert Solution

Introduction:

We all know that ,cancer is an abnormal growth and uncontrolled division of cells that spreads in the body and surrounding tissue. Cancerous cells have lost the property of contact inhibition due to which they show uncontrolled growth. There are different approaches for treatment of cancer which includes surgery, radiation therapy , immunotherapy and chemotherapy.

Immunotherapy involves the use of anticancer immunological defence mechanism. Substance such as Alpha interferon are given which activate immune system and destroy tumors. Anti-telomerase is also an immunotherapy which helps in destruction of cancerous cells.