What is the mechanism by which microtubules can rapidly shrink, or undergo "catastrophe"? A At low levels of GTP, tau proteins are phosphorylated and bind to the microtubule to destabilize the + end. B At low levels of GTP, beta-tubulin subunits at the + end of the microtubule hydrolyze GTP, undergo a conformational change, and destabilize the filament so that the filament starts to disassemble
Proteins
We generally tend to think of proteins only from a dietary lens, as a component of what we eat. However, they are among the most important and abundant organic macromolecules in the human body, with diverse structures and functions. Every cell contains thousands and thousands of proteins, each with specific functions. Some help in the formation of cellular membrane or walls, some help the cell to move, others act as messages or signals and flow seamlessly from one cell to another, carrying information.
Protein Expression
The method by which living organisms synthesize proteins and further modify and regulate them is called protein expression. Protein expression plays a significant role in several types of research and is highly utilized in molecular biology, biochemistry, and protein research laboratories.
QUESTION 4
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What is the mechanism by which microtubules can rapidly shrink, or undergo "catastrophe"?
A At low levels of GTP, tau proteins are phosphorylated and bind to the microtubule to destabilize the + end.
B At low levels of GTP, beta-tubulin subunits at the + end of the microtubule hydrolyze GTP, undergo a conformational change, and destabilize the filament so that the filament starts to disassemble from the + end.
C At low levels of ATP, tubulin subunits are not added to the + end of the microtubule.
D At low levels of ATP, the microtubules rapidly disassemble since ADP-bound tubulin subunits are lost at both the + and - ends of the filament.
E At high levels of GTP, tubulin subunits are more quickly added to the - end than to the + end of the microtubule, resulting in the shrinking of the + end of the microtubule.
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