What is the appropriate sequence of reagents to accomplish the following synthesis? Your answer should have the letters and or numbers in sequence with no spaces or commas (eg. af3d) Reagents a. HCI b. HBr C HO, H,SO, d. Br e. O 1. H. Pd 9 Br, H0 h. C. H0 i Os0, then NaHSO, I HolOAc. HO then NaBH, 3. CH,CH,CH,Br k BH, then H,O, NaOH Qthen (CHS m. 2 equivalents of NaNH, n H. Lindar's catalyst O. Na / NH, P HSO,. Hoso, 4 (a),BH then HO, NaOH r. 1 equivalent of NaNH, 1. CH,Br 2. CH,CH,Br 4. CH,CH,CH,CH,Br 5. CH.CH.CH.CH.CH.Br
What is the appropriate sequence of reagents to accomplish the following synthesis? Your answer should have the letters and or numbers in sequence with no spaces or commas (eg. af3d) Reagents a. HCI b. HBr C HO, H,SO, d. Br e. O 1. H. Pd 9 Br, H0 h. C. H0 i Os0, then NaHSO, I HolOAc. HO then NaBH, 3. CH,CH,CH,Br k BH, then H,O, NaOH Qthen (CHS m. 2 equivalents of NaNH, n H. Lindar's catalyst O. Na / NH, P HSO,. Hoso, 4 (a),BH then HO, NaOH r. 1 equivalent of NaNH, 1. CH,Br 2. CH,CH,Br 4. CH,CH,CH,CH,Br 5. CH.CH.CH.CH.CH.Br
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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![### Synthesis Problem
**Objective:** Determine the appropriate sequence of reagents to achieve the following chemical synthesis transformation.
**Transformation:**
Aromatic ring with a terminal alkyne to an aromatic ring with a linear alkane side chain.
**Reagents List:**
- **a.** HCl
- **b.** HBr
- **c.** \[Br_2, H_2SO_4\]
- **d.** \[Br_2\]
- **e.** Cl_2
- **f.** \[Cl_2, hv\]
- **g.** Na, NH_3
- **h.** \[H_2, Lindlar's catalyst\]
- **i.** NaNH_2
- **j.** \[H_2SO_4, H_2O\]
- **k.** \[(sia)_2BH then H_2O_2, NaOH\]
- **l.** \[BH_3 then H_2O_2, NaOH\]
- **m.** 2 equivalents of NaNH_2
- **n.** 1 equivalent of NaNH_2
- **o.** \[O_3 then NaHSO_3\]
- **p.** \[H_2O, H+\]
- **q.** \[Hg(OAc)_2, H_2O then NaBH_4\]
- **r.** \[O_3 then (CH_3)_2S\]
**Organic Fragments List:**
1. CH_3Br
2. CH_2CH_2Br
3. CH_3CH_2CH_2Br
4. CH_3(CH_2)_3Br
5. CH_3(CH_2)_4Br
### Diagram Description:
- **Initial Structure:** An aromatic ring (benzene) attached to a terminal alkyne group.
- **Final Structure:** An aromatic ring (benzene) with a five-carbon linear alkane side chain.
**Instructions for Solution:**
Investigate the appropriate numbering of reagents and fragments to convert the initial aromatic alkyne to the desired aromatic alkane with the specified five-carbon chain using the provided list. The answer should be a string of letters and/or numbers indicating the sequence of reagents or fragments](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F23029c3f-32e4-4946-9f07-7f9c026ab9f8%2F0e74277c-fb5e-44d7-b3fd-99376b339bbd%2Fyvnw2sb_processed.png&w=3840&q=75)
Transcribed Image Text:### Synthesis Problem
**Objective:** Determine the appropriate sequence of reagents to achieve the following chemical synthesis transformation.
**Transformation:**
Aromatic ring with a terminal alkyne to an aromatic ring with a linear alkane side chain.
**Reagents List:**
- **a.** HCl
- **b.** HBr
- **c.** \[Br_2, H_2SO_4\]
- **d.** \[Br_2\]
- **e.** Cl_2
- **f.** \[Cl_2, hv\]
- **g.** Na, NH_3
- **h.** \[H_2, Lindlar's catalyst\]
- **i.** NaNH_2
- **j.** \[H_2SO_4, H_2O\]
- **k.** \[(sia)_2BH then H_2O_2, NaOH\]
- **l.** \[BH_3 then H_2O_2, NaOH\]
- **m.** 2 equivalents of NaNH_2
- **n.** 1 equivalent of NaNH_2
- **o.** \[O_3 then NaHSO_3\]
- **p.** \[H_2O, H+\]
- **q.** \[Hg(OAc)_2, H_2O then NaBH_4\]
- **r.** \[O_3 then (CH_3)_2S\]
**Organic Fragments List:**
1. CH_3Br
2. CH_2CH_2Br
3. CH_3CH_2CH_2Br
4. CH_3(CH_2)_3Br
5. CH_3(CH_2)_4Br
### Diagram Description:
- **Initial Structure:** An aromatic ring (benzene) attached to a terminal alkyne group.
- **Final Structure:** An aromatic ring (benzene) with a five-carbon linear alkane side chain.
**Instructions for Solution:**
Investigate the appropriate numbering of reagents and fragments to convert the initial aromatic alkyne to the desired aromatic alkane with the specified five-carbon chain using the provided list. The answer should be a string of letters and/or numbers indicating the sequence of reagents or fragments

Transcribed Image Text:**Question 4 (3 points)**
Rank the following in order of stability, from most stable = 1 to least stable = 4:
1. The first diagram shows a cyclohexane ring with an ethyl group attached.
2. The second diagram shows a cyclohexene ring with a single double bond.
3. The third diagram shows a cyclohexadiene ring with two double bonds.
4. The fourth diagram shows a methylcyclohexene ring with a double bond.
Each diagram is accompanied by a dropdown menu for selecting the rank.
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