What drives the transport of fatty acids for b-oxidation into themitochondrial matrix?The hydrolysis of two phosphate bonds from ATP to AMPand two inorganic phosphate.The transfer of CoASH to fatty acidsThe substitution reactions involving COASH and Carnitine inthe inner membrane space.An increase in fatty acid concentration in the cytosol duringthe post-absorptive (fasting state).All of these

The transport of fatty acids from Cytosol into the mitochondrial matrix occurs by carnitine shuttle…

Answered: What drives the transport of fatty…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Breakdown of fatty acids for energy produces two-carbon fragments that are converted to acetyl CoA molecules. How would these molecules be metabolized in aerobic cellular respiration? They would directly enter the energy-yielding phase of glycolysis. They would directly enter the electron transport chain. They would directly enter the citric acid cycle. They would be fermented in the cytoplasm. They would be converted to pyruvate and then undergo pyruvate oxidation upon transport into mitochondria.
Which is both an input and an output of a metabolic pathway? Acetyl-CoA Oxaloacetate Citrate GTP
The metabolic function of the pentose phosphate pathway is: act as a source of ADP biosynthesis provide intermediates for the citric acid cycle. generate NADPH and pentoses for the biosynthesis of fatty acids and nucleic acids. O participate in oxidation-reduction reactions during the formation of H2O.
Which of the following conditions must be met within the cell In order for the enzyme pyruvate carboxylase to be activated? Select all that apply. NADP+ levels must be high Phosphofructokinase must be in the activated R-state Beta-oxidation of fatty acids happening in the mitochondrial matrix AMP levels must be high ATP levels must be high
Dinitrophenol (DNP) is a lipid soluble H+ binding drug that equalizes the H+ concentration across the inner mitochondrial membrane. Which of the following would you predict to occur upon addition of DNP to a cell? Halt in both pyruvate oxidation and ATP synthesis Halt in pyruvate oxidation and continuation in ATP synthesis Continuation in pyruvate oxidation and halt in ATP synthesis Continuation in both pyruvate oxidation and ATP synthesis
Of eight enzymes in the CAC, why is the succinate dehydrogenase complex unique? Because it is a component of the electron transport chain Because it catalyzes an oxidative reaction Because it is an integral membrane protein All of the above Only A and C
Calcium is an important regulator of the citric acid cycle. Calcium is transported across the mitochondrial inner membrane by a Ca²- 2+ uniporter that is driven by the negative potential inside the matrix. Part A Assuming a membrane potential across the inner membrane of 172 mV (inside negative), calculate the ratio of the [Ca2+] in the matrix to that in the cytoplasm ([Ca2+]m/[Ca²+]c) that would exist at equilibrium (i.e., AG = 0). Express your answer using two significant figures. [Ca2+]m [Ca2+] = ΤΟ ΑΣΦ Submit Request Answer Part B ? Cytoplasmic [Ca2+] is on the order of 10-7 M in a healthy cell. Based on your answer in Part A, calculate the [Ca2+] that would exist in the matrix at equilibrium. Express your answer to two significant figures and include the appropriate units. ☐ μÅ ? Value Units
Cyanide toxicity results from its ability to inhibit cytochrome oxidase c, part of the ETC of cell respiration. What effect(s) might you expect from cyanide poisoning? U a. Intracellular accumulation of NADH. Ob. Rapid depletion of oxygen. Increased amounts of oxidative phosphorylation. Od. Inhibition of PFK would occur. U e. Decreased production of ATP
The alternative fate of pyruvate in the mitochondrial matrix is the conversion of pyruvate to __________ catalyzed by __________________ ? Oxaloacetate, pyruvate carboxylase Alanine, alanine aminotransferase Lactate, Lactate dehydrogenase Acetyl-Co, PDHC
Taking in consideration glycolysis, the pyruvate dehydrogenase complex, and the citric acid cycle, how many FAD molecules are reduced from a single molecules of glucose 2 FAD 4 FAD 1 FAD 3 FAD None of the above

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