What concentrations of acetic acid (pKa=4.76)(pKa=4.76) and acetate would be required to prepare a 0.10 M0.10 M buffer solution at pH 4.9pH 4.9 ?
What concentrations of acetic acid (pKa=4.76)(pKa=4.76) and acetate would be required to prepare a 0.10 M0.10 M buffer solution at pH 4.9pH 4.9 ?
Strategy
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Rearrange the Henderson–Hasselbalch equation to solve for the ratio of base (acetate) to acid (acetic acid), [A−]/[HA][A−]/[HA] .
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Use the mole fraction of acetate to calculate the concentration of acetate.
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Calculate the concentration of acetic acid.
Step 1: The ratio of base to acid is 1.41.4 .
Step 2: The mole fraction of acetate is 0.580.58 , and the concentration of acetate is 0.0580.058 .
Step 3: Calculate the concentration of acetic acid.
That is, there are 1.4 molecules1.4 molecules of acetate for each molecule of acetic acid.
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