What are the possible sources of errors or deviations between the theoretical and experimental pKa values for lysine?
Q: What is Ehler Danlos Syndrome (EDS)? What is the biochemical abnormality? What are the different…
A: Genes are responsible for the expressed characteristic of a cell. A mutation in the gene that is…
Q: 2,3-Bisphosphoglycerate lies in a central cavity within the hemoglobin tetramer, stabilizing the T…
A: BPG is present in the RBCs of human beings and other species. It is a highly charged anion. In…
Q: List two ways in which glutathione functions in red blood cells.
A: Glutathione is a tripeptide which means it is composed of three amino acids, namely- glycine,…
Q: What two factors determine the percent saturation of a binding site?
A: Percent saturation of a binding site is the percentage of ligand or drug which binds to the binding…
Q: How many high-phosphoryltransferpotential molecules are required to synthesize…
A: The cell membranes are composed of phospholipids, a complex class of lipids in which phosphate is…
Q: In what general ways is balance of Ca21 achieved in the blood?
A: Calcium is of crucial importance in our body. It has several roles to play such as- Contraction…
Q: Aspartate amino acids' pI values can be calculated as follows:
A: Aspartic acid is a standard amino acid and has a carboxylic group in its side chain. Due to the…
Q: technique is used to identify the binding partner for Izumo?
A: Sexual reproduction helps in the increase in progeny of almost all eukaryotic organisms. Sperm meets…
Q: What is the Source of Cyclic AMP (cAMP)?
A: Adenosine triphosphate is also known as ATP, is the molecule that plays the role in carrying the…
Q: What are thymine-thymine dimers?
A: Deoxyribonucleic acid (DNA) is the hereditary material in humans and almost all other organisms,…
Q: What are the differences between synthesis of phosphatidylethanolamine in prokaryotes and…
A: Glycerol is a polyol compound that is made up of more than one hydroxyl group. Glycerol is a…
Q: What is Cohesin Complex?
A: DNA ( deoxyribonucleic acid) is the genetic material that the organism inherits from the parental…
Q: Define the term Allosteric Modulation?
A: The word, Allosteric, is derived from the Greek language in which Allos meaning 'other' and stereos…
Q: Transition-state analogs, which can be used as enzyme inhibitors and to generate catalytic…
A: Compounds resembling the transition state of a catalyzed reaction should be very effective…
Q: Discuss the Pharmacokinetics of morphine sulfate using the correct sequence you have chosen in…
A: Morphine is a drug that targets a specific type of receptor that affects multiple processes. It does…
Q: Hydroxyurea has been shown to increase the expression of fetal hemoglobin in adult red blood cells,…
A: Sickle cell anemia is the disorder in which abnormality in oxygen carrying hemoglobin present in red…
Q: What biochemical changes are required to convert tyrosine to (a) norepinephrine and (b)…
A: Much of the tyrosine is catabolized for energy production instead of getting incorporated into…
Q: The T-state of hemoglobin is favored over the R-state in blood under which of the listed conditions?
A: Introduction: Hemoglobin is the most abundant porphyrin-containing compound in red blood cells…
Q: What two types of defensins contribute to the biochemical barrier?
A: Biochemical barriers are the chemical molecules synthesized within the body that act as a defence…
Q: what is the standard of FTIR in pectin?
A: Infrared spectroscopy analyses the samples by infrared spectrum. The infrared absorption of…
Q: 63 Neonatal hyperbilirubinemia is usually treated with phototherapy, resulting in prompt reduction…
A: Introduction Jaundice is an illness in which a high level of bilirubin, a yellow-orange bile…
Q: the key features between glycosaminoglycan-binding proteins and lectins?
A: Glycosaminoglycans (GAGs) are mucopolysaccharides containing a large number of disaccharide units…
Q: what are Cohesin Complexes ?
A: A sequence of events occurring in a cell, which causes the cell to divide and forms two daughter…
Q: After being stabilized with supplemental oxygen, a blood transfusion, and medication to help with…
A: Hydroxyurea: It is a class of antimetabolites. This class of drug is used to treat cancer. It is a…
Q: Deficiencies of the components of Complexes I, III, and IV tend to have severe physiological…
A: The complex I, II, III, IV, and V are the cytochrome complexes that are part of the oxidative…
Q: What is the chemical equation of benedict's test for traceable levels of reducing sugars in blood?
A: The presence of any reducing sugar in an analyte can be detected using Benedict's test. The reagent…
Q: Estimate the binding affi nity of a ligand for its receptor from the followingdata:
A: The receptor is a protein that is found on the cell surface. These receptors bind to the ligand with…
Q: How Are Thymine Nucleotides Synthesized?
A: Nucleotides are compounds composed of a phosphate and nucleoside. They act as a monomer of the…
Q: Why Valinomycin is highly selective for K+ relative to Na+?
A: Valinomycin is a naturally occurring dodecadepsipeptide used in the transport of potassium and as an…
Q: f a commercially available insulin preparation contains 1 ppm of proinsulin, how many micrograms of…
A: Glucose is a carbohydrate, which provides instant energy to the body for carrying out the various…
Q: What is cyclic AMP (cAMP)?
A: a. The second messenger is short intracellular signaling molecules that are released by the cell to…
Q: What is the dominant biochemical activity or molecular interaction that Sickle Cell Anemia…
A: Hemoglobin is an oligomeric conjugated protein with four peptide chains joined by a…
Q: What would be the effect of adequate concentration of AMP andGMP?
A: AMP: Adenosine Monophosphate GMP: Guanosine Monophosphate
Q: Individuals with phenylketonuria cannot convert phenylalanine to tyrosine. Why don’t these…
A: Inborn errors of metabolism are uncommon hereditary (inherited) disorders in which the body can't…
Q: What are the thioesters in the reaction catalyzed by PDH complex?
A: Thioesters in the reaction catalysed by PDH Complex are : Acetyllipoamide AcetylCoenzyme A
Q: What fragments can be obtained from the treatment of Pro-Lys-Gly-Gly-Arg-Trp-His-Cys with trypsin…
A: The digestive enzymes trypsin and chymotrypsin are secreted by the pancreas as inactive enzyme…
Q: The affinity of hemagglutinin for sialic acid is quite low, with a Kd of approximately 5 mM. How…
A: Sialic acid is found in cell surface receptors of the host cells and it can be either a ganglioside…
Q: Is there a way to classify or identify the tests needed in order to differentiate C12H22O11 and…
A: C12H22O11 is known as sucrose. It is a disaccharide sugar, formed by glucose and fructose. It is…
Q: What do the peaks of C6H12O2 show?
A: The peaks of the substance under study are obtained after using the bio technique f NMR. Nuclear…
Q: why is there a difference between the stock solution concetration of chymotrypsin calculated from…
A: Stock concentration is the concentration of biomolecule which is prepared and dilutions where done…
Q: What is the relationship between beta amyloid and APP?
A: Brain cells that process, store, and retrieve information degenerate and die in Alzheimer's disease.
Q: Bisphosphoglycerate lies in a central cavity within the hemoglobin tetramer, stabilizing the T…
A: Hemoglobin (Hb) is the protein complex, which is a tetramer in a structure that binds to the oxygen…
Q: What are the penetranceand the expressivity of agene?
A: A gene is a sequence of nucleotides in genome that codes for a functioning molecule. There is…
Q: How does fructose-2,6- bisphosphate play a role as an allosteric effector?
A: A molecule that binds to an enzyme and causes allosteric effects is known as an "allosteric…
Q: By what the two polypeptides of human insulin are linked together?
A: Insulin is peptide hormone secreted by pancreatic cells that is responsible for reduction of blood…
Q: Explain how the pKa for histidine 57 is important to its role in the mechanism of chymotrypsin…
A: Chymotrypsin is a digestive enzyme found in pancreatic juice that conducts proteolysis, or the…
Q: What are the two most common cofactor types?
A: A cofactor is a non-protein chemical molecule or metallic ion needed for an enzyme's catalytic…
What are the possible sources of errors or deviations between the theoretical and
experimental pKa values for lysine?
Trending now
This is a popular solution!
Step by step
Solved in 2 steps
- 11.96 Is there a crude association between either measure of adiposity (BMI, WHR), considered separately, and serum estradiol?The plasma profiles of codeine (COD) and metabolites for 2 individuals (labeled A and B) are shown below. The X-axis is time in hours after an oral dose of codeine. [M=morphine; C6G=COD-6-glucuronide; M3G = morphine-3-glucuronide; NM (ignore)]. Note the data is shown on a log scale on the Y-axis. (A) Which individual is the poor metabolizer? Explain how you know this from the profiles? (B) Is this a problem for cough suppression? Explain. -CH HO Codeine COD 10 000 1000 C6G COD 100 M3G M6G NM 10 M 10 20 30 0 10 20 30 Plasma concentration (nmol I-)CYP2E1 has a much higher Km for ethanol than ADH (11 mM versus 0.05 mM,respectively). When greater portions of ethanol are ingested (0.08% or 17 mM), which part of the statement would be true?
- Calculate the pI of the peptide KLMRDSP (pKa = 3.5, 3.9, 9.5, 10.0, 12.5).What is Ehler Danlos Syndrome (EDS)? What is the biochemical abnormality? What are the different types of EDS and their clinical manifestations? What is the management of this disease?Is there a reason why you divided the pKa's by 2 when determining the pI?
- When the amino acid sequences of insulin isolated from differentorganisms were determined, some differences were noted.For example, alanine was substituted for threonine, serine wassubstituted for glycine, and valine was substituted for isoleucineat corresponding positions in the protein. List the single-basechanges that could occur in triplets to produce these amino acidchanges.What is the dominant biochemical activity or molecular interaction that Sickle Cell Anemia Hemoglobin Subunit beta-protein (P68871) is predicted to carry out?Suggest the effects of each of the following mutations on the physiologicalrole of chymotrypsinogen:(a) R15S(b) C1S(c) T147S
- Can you please help me how to draw tripeptide ile-leu-arg and indicate the torsion angles phi and psi for leucine?The affinity of hemagglutinin for sialic acid is quite low, with a Kd of approximately 5 mM. How does efficient attachment occur with such a low-affinity interaction?One can identify phenylketonurics and PKU carriers (heterozygotes) by means of a phenylalanine tolerance test. One injects a large dose of pheny- lalanine into the bloodstream and measures its clearance from the blood by measuring serum phenylalanine levels at regular intervals. Sketch curves showing relative blood phenylalanine concentration versus time that you would expect to be displayed by (a) a PKU patient, (b) a heterozygote, and (c) a normal individual. What kind of tolerance test could you devise to distinguish between PKU resulting from either phenylalanine hydroxylase deficiency or dihydropteridine reductase deficiency?