What amino acids will be positive at a pH of 2? Use the pKa table TABLE 5.1 Properties of the common amino acids found in proteinspK₂ of a-COOHGroupªNameAlanineArginineAsparagineAspartic acidCysteineGlutamineGlutamic acidGlycineHistidineIsoleucineLeucineLysineMethioninePhenylalanineProlineSerineThreonineTryptophanAbbreviations: 1-and 3-letter codesA, AlaR, ArgN, AsnD, AspC, CysQ, GinE, GluG, GlyH, HisI, lleL, LeuK, LysM, MetF, PheP, ProS, SerT, ThrW, TrpY, TyrV, Val2.32.22.02.11.82.22.22.31.82.42.42.22.31.82.02.22.62.42.22.3pK₂ of a-NH3Groupª9.79.08.89.810.89.19.79.69.29.79.69.09.29.110.69.210.49.49.19.6pK₂ of lonizingSide Chainª12.53.98.34.26.010.010.1Residue Mass(daltons)71.08156.20114.11115.09103.14128.14129.1257.06137.15113.17113.17128.18131.21147.1897.1287.08101.11186.21163.1899.14Occurrence inProteins (mol %)8.75.04.25.91.33.76.67.92.45.58.95.52.04.04.75.85.61.53.57.2

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Biochemistry

What amino acids will be positive at a pH of 2? Use the pKa table

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Question

What amino acids will be positive at a pH of 2? Use the pKa table

TABLE 5.1 Properties of the common amino acids found in proteins
pK₂ of a-COOH
Groupª
Name
Alanine
Arginine
Asparagine
Aspartic acid
Cysteine
Glutamine
Glutamic acid
Glycine
Histidine
Isoleucine
Leucine
Lysine
Methionine
Phenylalanine
Proline
Serine
Threonine
Tryptophan
Abbreviations: 1-
and 3-letter codes
A, Ala
R, Arg
N, Asn
D, Asp
C, Cys
Q, Gin
E, Glu
G, Gly
H, His
I, lle
L, Leu
K, Lys
M, Met
F, Phe
P, Pro
S, Ser
T, Thr
W, Trp
Y, Tyr
V, Val
2.3
2.2
2.0
2.1
1.8
2.2
2.2
2.3
1.8
2.4
2.4
2.2
2.3
1.8
2.0
2.2
2.6
2.4
2.2
2.3
pK₂ of a-NH3
Groupª
9.7
9.0
8.8
9.8
10.8
9.1
9.7
9.6
9.2
9.7
9.6
9.0
9.2
9.1
10.6
9.2
10.4
9.4
9.1
9.6
pK₂ of lonizing
Side Chainª
12.5
3.9
8.3
4.2
6.0
10.0
10.1
Residue Mass
(daltons)
71.08
156.20
114.11
115.09
103.14
128.14
129.12
57.06
137.15
113.17
113.17
128.18
131.21
147.18
97.12
87.08
101.11
186.21
163.18
99.14
Occurrence in
Proteins (mol %)
8.7
5.0
4.2
5.9
1.3
3.7
6.6
7.9
2.4
5.5
8.9
5.5
2.0
4.0
4.7
5.8
5.6
1.5
3.5
7.2

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