We modeled Cystic Fibrosis in lab. What is the main problem with someone with Cystic Fibrosis? What ion is involved and what happens as a result of this ion? Be specific.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
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**Modeling Cystic Fibrosis in the Lab**

**Question 6:**

We modeled Cystic Fibrosis in the lab. What is the main problem with someone with Cystic Fibrosis? What ion is involved and what happens as a result of this ion? Be specific. 

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The main problem in individuals with Cystic Fibrosis is the malfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This defect affects the transportation of chloride ions across cell membranes. As a result, thick mucus builds up in various organs, particularly the lungs and digestive system, leading to severe respiratory and digestive issues.
Transcribed Image Text:**Modeling Cystic Fibrosis in the Lab** **Question 6:** We modeled Cystic Fibrosis in the lab. What is the main problem with someone with Cystic Fibrosis? What ion is involved and what happens as a result of this ion? Be specific. --- The main problem in individuals with Cystic Fibrosis is the malfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This defect affects the transportation of chloride ions across cell membranes. As a result, thick mucus builds up in various organs, particularly the lungs and digestive system, leading to severe respiratory and digestive issues.
Expert Solution
Step 1 introduction

Cystic Abrosis is a multi-sysem Autosomal recessive disorder (GIT, Respiratory system 
Genito-urinary, sweat glands are affected).
One of the most common life limiting genetic disorder.

Seen mostly in western population. Cases continue to increase in India as well.

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