This drug resembles proteins that are cut by enzymes that use water to break amide linkages in proteins. What type inhibitor would this drug be? HO competitive S OH H NH

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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**Educational Content on Enzyme Inhibitors**

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**Question:**

This drug resembles proteins that are cut by enzymes that use water to break amide linkages in proteins. What type of inhibitor would this drug be?

**Chemical Structure Description:**

The image displays a chemical structure of a drug that visually resembles protein substrates. It includes:

- A hexagonal benzene ring, indicating an aromatic compound.
- Complex arrangements of functional groups, including hydroxyl (-OH) groups, amide (CONH-) groups, and other typical organic chemical structures.
- A sulfur atom (S) suggesting the presence of a thioether or related sulfur-containing functional group.
  
**Answer Choices:**

- ○ Competitive
- ○ Non-competitive

**Explanation:**

In the context of enzymatic reactions, competitive inhibitors are those that resemble the enzyme's natural substrate and thus compete for binding at the active site. Non-competitive inhibitors, on the other hand, bind at a separate site and alter the enzyme's activity without directly competing with the substrate. Based on the information provided, this drug likely acts as a competitive inhibitor due to its structural resemblance to the enzyme's substrate.

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Transcribed Image Text:**Educational Content on Enzyme Inhibitors** --- **Question:** This drug resembles proteins that are cut by enzymes that use water to break amide linkages in proteins. What type of inhibitor would this drug be? **Chemical Structure Description:** The image displays a chemical structure of a drug that visually resembles protein substrates. It includes: - A hexagonal benzene ring, indicating an aromatic compound. - Complex arrangements of functional groups, including hydroxyl (-OH) groups, amide (CONH-) groups, and other typical organic chemical structures. - A sulfur atom (S) suggesting the presence of a thioether or related sulfur-containing functional group. **Answer Choices:** - ○ Competitive - ○ Non-competitive **Explanation:** In the context of enzymatic reactions, competitive inhibitors are those that resemble the enzyme's natural substrate and thus compete for binding at the active site. Non-competitive inhibitors, on the other hand, bind at a separate site and alter the enzyme's activity without directly competing with the substrate. Based on the information provided, this drug likely acts as a competitive inhibitor due to its structural resemblance to the enzyme's substrate. ---
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