The zinc(II) ion behaves as a Lewis acid. It is found in an enzyme called carboxypeptidase A. This enzyme catalyzed the hydrolysis of C-terminal peptide bonds of proteins. The zinc ion will accept the lone pair of electrons on the oxygen in the peptide linkage. Explain why this Lewis acid behavior would make the carbon atom more susceptible to reaction
The zinc(II) ion behaves as a Lewis acid. It is found in an enzyme called carboxypeptidase A. This enzyme catalyzed the hydrolysis of C-terminal peptide bonds of proteins. The zinc ion will accept the lone pair of electrons on the oxygen in the peptide linkage. Explain why this Lewis acid behavior would make the carbon atom more susceptible to reaction
Principles of Modern Chemistry
8th Edition
ISBN:9781305079113
Author:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Publisher:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Chapter23: Polymeric Materials And Soft Condensed Matter
Section: Chapter Questions
Problem 30AP
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The zinc(II) ion behaves as a Lewis acid. It is found in an enzyme called carboxypeptidase A. This enzyme catalyzed the hydrolysis of C-terminal peptide bonds of proteins. The zinc ion will accept the lone pair of electrons on the oxygen in the peptide linkage. Explain why this Lewis acid behavior would make the carbon atom more susceptible to reaction.
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