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The velocity of spike propagation is proportional to the following combination of factors:
1
a
C, V R„R,
m
Where a is the radius of the axon, Rm and R; are specific resistances of the membrane and the
internal buffer, respectively. If we double the radius and simultaneously increase the concentration
of salt inside the axon twice (i.e. R; decreases two times), by how many fold will the velocity
change?

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