The reverse aldol condensation is at the heart of the preparatory phase of glycolysis. A) Why is this reaction needed for the effective harvest of energy from glucose? In other words, why does the cell change the length of the glucose chain from one 6-carbon chain to two 3-carbon chains? B) The reverse aldol reaction requires a specific set of molecular features to be catalyzed. In Class I aldolases, this feature is governed by the chemistry of an active site lysine sidechain. In Class II aldolases, this feature is governed by the chemistry of an active site Zn?+ cation. Why are these features important in promoting the reverse aldol cleavage of fructose 1,6-bisphosphate (shown)? Midterm CHOPO,2- Fo HO- -H H- -OH H- FHO- CH2OPO,2

The reverse aldol condensation is at the heart of the preparatory phase of glycolysis. A) Why is this reaction needed for the effective harvest of energy from glucose? In other words, why does the cell change the length of the glucose chain from one 6-carbon chain to two 3-carbon chains? B) The reverse aldol reaction requires a specific set of molecular features to be catalyzed. In Class I aldolases, this feature is governed by the chemistry of an active site lysine sidechain. In Class II aldolases, this feature is governed by the chemistry of an active site Zn?+ cation. Why are these features important in promoting the reverse aldol cleavage of fructose 1,6-bisphosphate (shown)? Midterm CHOPO,2- Fo HO- -H H- -OH H- FHO- CH2OPO,2

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

Give an example of a proline-catalyzed direct asymmetric aldol reaction
Please give mechanism for the acyolin products formed during this reaction.
can someone explain please? thank you!
Under the Classification of Mechatronic Products, provide at least 2 examples for each class and explain why such product belongs to a particular class.
19) What is the final product of the following Hofmann degradation reaction? What is the structure and general name of the intermediate that is involved? H3C NaOH / H,O / Br, H3C `NH2
Which of the following is true concerning the cyclization of sugar? The nucleophilic alchol group attracts the electrophilic Aldehyde or ketone group Cyclization always produecs a ring with a reducing end The carbon attached to the alcohol group becomes the anomeric carbon All of the above None of the above
Draw the product please and explain
Answer perfectly
2. Using arrow formalism, draw the reaction mechanism for the steps of glycolysis specified below. a. hexokinase: glucose B glucose 6P b. phosphoglucoisomerase: glucose 6P + fructose 6P c. aldolase: fructose 1,6 diphosphate B dihydroxyacetone phosphate + glyceraldehyde 3 phosphate d. triosephosphate isomerase: DHAP + GAP
In the 1st reaction of citric acid cycle, acetyl CoA and oxaloacetate are combined to form citrate as shown below. What is the best way to describe this reaction? CH acetyl Col CH₂ co exaloncertate HO citrate synthase ço, CH₂ HO-C-00 CH₂ co₂ citrate O It begins with an Aldol reaction followed by hydrolysis of CoA thioester). It begins with a keto-enol tautomerization followed by an Aldol reaction. It involves a Claisen condentation. OIt involves an Aldol condensation. None of the above
What is the mech for an acid catalyzed keto-enol interconversion?
Draw the complete electron pushing mechanism for the following transformation.