1. Glycosyltransferases (GT's) utilize NDP-sugars (nucleotide diphosphate sugars) as the glycosyl donors, such as UDP-glucose in glycogenesis. Consider UDP (circled in the box) acts as a leaving group and the original glycogen acts as a nucleophile. What could be the possible mechanism for the additional glucose to be incorporated onto the original glycogen? UDP-glucose HO40- OH (a) SN1 (b) SN2 (c) E1 (d) E2 glucose HO OH OH O. Original glycogen OH OH 0=8-6 0=2-0 UDP -0- OH OH GT NH OH Halaa) OH UDP-glucose O-UDP OH OH OH "One additional glucose

1. Glycosyltransferases (GT's) utilize NDP-sugars (nucleotide diphosphate sugars) as the glycosyl donors, such as UDP-glucose in glycogenesis. Consider UDP (circled in the box) acts as a leaving group and the original glycogen acts as a nucleophile. What could be the possible mechanism for the additional glucose to be incorporated onto the original glycogen? UDP-glucose HO40- OH (a) SN1 (b) SN2 (c) E1 (d) E2 glucose HO OH OH O. Original glycogen OH OH 0=8-6 0=2-0 UDP -0- OH OH GT NH OH Halaa) OH UDP-glucose O-UDP OH OH OH "One additional glucose

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Draw the structure of alpha-d-glucopyranose in straight chain cyclic, Haworth and cyclohexane-chair format. Draw the structures of two aldohexoses which are diastereomers but not epimers
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1. The reaction catalyzed by aldolase splits fructose-1,6-bisphosphate (F16BP) into glyceraldehyde-3-phosphate (G3P) and dihydroxyacetone phosphate (DHAP). The AG°" for the reaction is 23.8 kJ/mole. If the concentrations of G3P and DHAP are 2.5 mM and 1 mM, respectively, what concentration of F16BP is needed for the reaction to be at equilibrium in a human cell?
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1. Carbohydrates classification. 2. Write down the reactions: a) α,D-Glucopyranose + C2H5OH → b) D-Glucose + [Ag(NH3)2]+ → c) D-Glucopyranose + (CH3CO)2 O → d) D-Glucopyranose + CH3I → e) D-Glucose + HNO3 → f) D-Glucose + H2 → g) Lactose formation h) Sucrose hydrolysis 3. Write down the formula of β,D-galactopyranose
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