The observation that schizophrenia is associatedwith duplications of a certain copy number variant(CNV), while autism spectrum disorders areassociated with deletions of the same CNV,suggests thatboth disorders have an environmental componentneither disorder has a genetic componentboth disorders have identical phenotypesCNV mutations are present in all psychiatric disordersboth disorders share common developmentalpathways

CNV has been observed in various disorders like AUTISM SPECTRUM DISORDER, SCHIZOPHRENIA,…

Answered: The observation that schizophrenia is…

The observation that schizophrenia is associated with duplications of a certain copy number variant (CNV), while autism spectrum disorders are associated with deletions of the same CNV, suggests that

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter18: Genetics Of Behavior

Section: Chapter Questions

Problem 1CS: Why do you think it has been so difficult to identify genes underlying schizophrenia? Rachel asked...

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Why do you think it has been so difficult to identify genes underlying schizophrenia? Rachel asked to see a genetic counselor because she was concerned about developing schizophrenia. Her mother and maternal grandmother both had schizophrenia and were institutionalized for most of their adult lives. Rachels three maternal aunts are all in their 60s and have not shown any signs of this disease. Rachels father is alive and healthy, and his family history does not suggest any behavioral or genetic conditions. The genetic counselor discussed the multifactorial nature of schizophrenia and explained that many candidate genes have been identified that may be mutated in individuals with the condition. However, a genetic test is not available for presymptomatic testing. The counselor explained that based on Rachels family history and her relatedness to individuals who have schizophrenia, her risk of developing it is approximately 13%. If an altered gene is in the family and her mother carries the gene, Rachel has a 50% chance of inheriting it.
The Enhancingg Neuro Imaging Genetics Through Meta Analysis (ENIGMA) group is an international collaboration that has investigated MRI images of people with O autism spectrum disorder O major depressive disorder O general anxiety disorder Obipolar affective disorder Oschizopluenia,
in 1 to 2 paragraphs, describe the clinical course of schizophrenia
Tony has schizophrenia. He believes that he is the only true male on earth and that people don't really die, they just became other people, always female. Tony hears voices that say "Now he dies" and "Here's where he gets hurt." In addition, he reports having visual disturbances such as seeing streaks of light and after-images of people when they are no longer physically present. Based on these examples, Tony appears to suffer from schizophrenia, which is most strongly associated with O Type I; abnormal neurotransmitter activity O Type Il; abnormal neurotransmitter activity O Type I; abnormal brain structure O Type II; abnormal brain structure
Identical twins have an increased risk of developing schizophrenia as compared to
Concordance value with MZ twins is 46% and DZ twins is 14% for schizophrenia. What does this mean in terms of genetic and environmental components underlying schizophrenia?
How is the experience of stigma self-perpetuated in those with schizophrenia? O Negative experiences of discrimination cause the individual to hide their diagnosis when meeting new people Feelings of stigma are exacerbated when medication regimens are not followed Stigma is mistakenly felt when true feelings of paranoia and injustice emerge The disease process distorts reality so that the stigma seems worse than it is Page 5 of 75 Previous Page Next Page W DEC
Diseases of the Nervous System Motor disorder caused by the death of dopamine- [ Choose ] secreting neurons in the midbrain. Characterized by tremors, slow movements, and rigidity. Disease in which people have a persistent lack of [ Choose ] interest or pleasure; may be typified by manic and depressive phases [Choose ] Immune system eats away at the myelin sheaths on Depression nerve cells Multiple Sclerosis Parkinsons Mental deterioration characterized by confusion and memory loss. Caused by the formation of plaques in the brain. Alzheimers Schizophrenia Characterized by hallucinations, delusions, multiple [ Choose ] personalities, possible genetic linkages
One difference between Huntington's disease and the other three neurodegenerative disorders discussed (AD, PD, ALS) is that Huntington's disease: 1) is usually spontaneous 2) is usually autosomal recessive 3) has nucleotide (CAG) repeats 4) occurs later in life
Discuss what we know about both of the two main hypotheses (potential targets) for the origin of schizophrenia. LTP is the part of the learning process by which our synapses are strengthened. Using the example of hippocampal circuitry (LP can happen elsewhere in the brain), 1) draw and label the hippocampal circuitry, indicating the direction of the signaling, 2) describe the conditions required for LTP, and 3) draw a graph to show how EPSP magnitude is affected and explain what the long term implications are.
Which one is correct
1) Please explain the likelihood of Susan and Lisa developing Schizophrenia and Alzheimer’s. A) Susan tells you that her twin brother has just been diagnosed with schizophrenia. She wants to know her risk factors for developing the disorder. B) Lisa, a 55-year-old high school teacher, recently discovered that her mother has been diagnosed with Alzheimer’s disease at the age of 78. Alzheimer’s disease is a progressive brain disorder that impairs memory, thinking skills, and the ability to carry out simple tasks. Given her mother’s diagnosis and her own increasing forgetfulness, Lisa is concerned about her risk of developing Alzheimer’s disease and seeks counseling for guidance.