The hydrolysis of an amide often requires harsh conditions, hightemperatures, or a special enzyme. Identify which of the followingstatements does NOT provide a reason for this lack of reactivity.A) The pka of NH4+ is ~10 and thepka of H₂O is ~16.B) The nitrogen of the amide candonate electrons to make aresonance structure that stabilizesthe partial positive charge on thecarbon.C) -NH₂ is not as stable of aleaving group as -OH, since it isless electronegative.D) There is significant 'double-bond' character between thecarbon and nitrogen in an amide.

Solution: Amide is a class of neutral compounds having the general formula RCONH2.

Answered: The hydrolysis of an amide often…

The hydrolysis of an amide often requires harsh conditions, high emperatures, or a special enzyme. Identify which of the following statements does NOT provide a reason for this lack of reactivity.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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