OEt O OEt O i) Amine ОН HO, ii) H20 washing to remove the HCI residue N. i) What's the structure of Amine reagent? Amine structure ii) Why does not carboxyl acid react with amine? iii) Draw the mechanism of the reaction.

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Answer the following questions based on the information provided.
(a) Sildenafil (Viagra) is used to treat erectile dysfunction (impotence; inability to get
or keep an erection) in men. Sildenafil (Revatio) is used to improve the ability to
exercise in adults with pulmonary arterial hypertension. One of the key step of
Sildenafil synthesis is shown below.
OEt O
OEt O
i) Amine
HO
CHO
ii) H20 washing to remove the HCI residue
CI
N.
i)
What's the structure of Amine reagent?
Amine structure
ii)
Why does not carboxyl acid react with amine?
iii)
Draw the mechanism of the reaction.
Transcribed Image Text:Answer the following questions based on the information provided. (a) Sildenafil (Viagra) is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Sildenafil (Revatio) is used to improve the ability to exercise in adults with pulmonary arterial hypertension. One of the key step of Sildenafil synthesis is shown below. OEt O OEt O i) Amine HO CHO ii) H20 washing to remove the HCI residue CI N. i) What's the structure of Amine reagent? Amine structure ii) Why does not carboxyl acid react with amine? iii) Draw the mechanism of the reaction.
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