OEt O OEt O i) Amine ОН HO, ii) H20 washing to remove the HCI residue N. i) What's the structure of Amine reagent? Amine structure ii) Why does not carboxyl acid react with amine? iii) Draw the mechanism of the reaction.

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
icon
Related questions
icon
Concept explainers
Question
Answer the following questions based on the information provided.
(a) Sildenafil (Viagra) is used to treat erectile dysfunction (impotence; inability to get
or keep an erection) in men. Sildenafil (Revatio) is used to improve the ability to
exercise in adults with pulmonary arterial hypertension. One of the key step of
Sildenafil synthesis is shown below.
OEt O
OEt O
i) Amine
HO
CHO
ii) H20 washing to remove the HCI residue
CI
N.
i)
What's the structure of Amine reagent?
Amine structure
ii)
Why does not carboxyl acid react with amine?
iii)
Draw the mechanism of the reaction.
Transcribed Image Text:Answer the following questions based on the information provided. (a) Sildenafil (Viagra) is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Sildenafil (Revatio) is used to improve the ability to exercise in adults with pulmonary arterial hypertension. One of the key step of Sildenafil synthesis is shown below. OEt O OEt O i) Amine HO CHO ii) H20 washing to remove the HCI residue CI N. i) What's the structure of Amine reagent? Amine structure ii) Why does not carboxyl acid react with amine? iii) Draw the mechanism of the reaction.
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps with 2 images

Blurred answer
Knowledge Booster
Catalysis and Enzymatic Reactions
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Chemistry
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
Elementary Principles of Chemical Processes, Bind…
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY