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The Henry reaction is similar to what reaction you learned previously? Aldol condensation Robinson annulation Claisen condensation Michael reaction

The Henry reaction is similar to what reaction you learned previously? Aldol condensation Robinson annulation Claisen condensation Michael reaction

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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**Question: The Henry reaction is similar to what reaction you learned previously?** - ○ Aldol condensation - ○ Robinson annulation - ○ Claisen condensation - ○ Michael reaction This text appears as a part of a quiz section on an educational website focused on chemistry. The students are asked to identify which reaction the Henry reaction is similar to, among the listed options. There are no graphs or diagrams accompanying the text.
Transcribed Image Text:**Question: The Henry reaction is similar to what reaction you learned previously?** - ○ Aldol condensation - ○ Robinson annulation - ○ Claisen condensation - ○ Michael reaction This text appears as a part of a quiz section on an educational website focused on chemistry. The students are asked to identify which reaction the Henry reaction is similar to, among the listed options. There are no graphs or diagrams accompanying the text.
**Question: In the following reaction, which compound is the nucleophile?** ![Chemical Reaction Diagram] 1. **Reactants in the Chemical Reaction:** - **Compound (1):** A chemical compound featuring a benzene ring with two carbonyl groups (-C=O) attached at the 1 and 3 positions. It is labeled with a (1) and generally represents the target of the nucleophilic attack. - **Compound (2):** CH3NO2 (Nitromethane), which is the source of nucleophilic species when reacted with a base. - **Condition:** The reaction is taking place in the presence of NaOH (sodium hydroxide), a strong base. 2. **Process of the Reaction:** - Sodium hydroxide (NaOH) acts to deprotonate the nitromethane (CH3NO2), producing a nucleophilic nitronate anion. - This nitronate anion can then attack the electrophilic site in compound (1), typically at the carbonyl carbon. 3. **Multiple Choice Options:** - ○ 1 - ○ 3 - ○ 2 **Explanation:** - In the given multiple-choice question, students are asked to determine which compound serves as the nucleophile in the reaction. - Compound (2) – Nitromethane (CH3NO2), upon deprotonation by NaOH, becomes the nucleophile. **Correct Answer: 2** **Educational Notes:** - **Nucleophile:** A nucleophile is a chemical species that donates an electron pair to form a chemical bond in reaction. In this scenario, after deprotonation, the nitronate anion formed from nitromethane serves as the nucleophile. - **Electrophile:** Conversely, an electrophile is a species that accepts an electron pair. In this reaction, the carbonyl carbon of compound (1) likely serves as the electrophile. - **Base Role:** Sodium hydroxide acts as a base, facilitating the deprotonation necessary to generate the nucleophilic species.
Transcribed Image Text:**Question: In the following reaction, which compound is the nucleophile?** ![Chemical Reaction Diagram] 1. **Reactants in the Chemical Reaction:** - **Compound (1):** A chemical compound featuring a benzene ring with two carbonyl groups (-C=O) attached at the 1 and 3 positions. It is labeled with a (1) and generally represents the target of the nucleophilic attack. - **Compound (2):** CH3NO2 (Nitromethane), which is the source of nucleophilic species when reacted with a base. - **Condition:** The reaction is taking place in the presence of NaOH (sodium hydroxide), a strong base. 2. **Process of the Reaction:** - Sodium hydroxide (NaOH) acts to deprotonate the nitromethane (CH3NO2), producing a nucleophilic nitronate anion. - This nitronate anion can then attack the electrophilic site in compound (1), typically at the carbonyl carbon. 3. **Multiple Choice Options:** - ○ 1 - ○ 3 - ○ 2 **Explanation:** - In the given multiple-choice question, students are asked to determine which compound serves as the nucleophile in the reaction. - Compound (2) – Nitromethane (CH3NO2), upon deprotonation by NaOH, becomes the nucleophile. **Correct Answer: 2** **Educational Notes:** - **Nucleophile:** A nucleophile is a chemical species that donates an electron pair to form a chemical bond in reaction. In this scenario, after deprotonation, the nitronate anion formed from nitromethane serves as the nucleophile. - **Electrophile:** Conversely, an electrophile is a species that accepts an electron pair. In this reaction, the carbonyl carbon of compound (1) likely serves as the electrophile. - **Base Role:** Sodium hydroxide acts as a base, facilitating the deprotonation necessary to generate the nucleophilic species.
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