The graph shows a tracing of membrane potential change during the course of an action potential in a typical neuron. Predict the effect of exposure to the following neurotoxins. Briefly explain how you would expect the action potential to change in the presence of each toxin and why.A toxin produced by puffer fish which specifically binds to voltage-gated sodium channels and blocks the flow of sodium ions through the channel. A toxin found in scoprion venom which slows the closure of voltage-gated sodium channel inactivation gates. Assume that the cell is normally brought to threshold by an electrical stimulus applied to it, so that any change is due only to the presence of the toxinPrecise values for voltage and duration are not important, just a general trend in how the action potential may differ from the typical trace shown is expected. +25-25-50-75time (msec)membrane potential (mV)

:Both graded potential and action potential are able to generate membrane depolarizations of the…

Answered: The graph shows a tracing of membrane…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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The graph shows a tracing of membrane potential change during the course of an action potential in a typical neuron. Predict the effect of exposure to the following neurotoxins. Briefly explain how you would expect the action potential to change in the presence of each toxin and why.

1. A toxin produced by puffer fish which specifically binds to voltage-gated sodium channels and blocks the flow of sodium ions through the channel.
2. A toxin found in scoprion venom which slows the closure of voltage-gated sodium channel inactivation gates.

Assume that the cell is normally brought to threshold by an electrical stimulus applied to it, so that any change is due only to the presence of the toxin
Precise values for voltage and duration are not important, just a general trend in how the action potential may differ from the typical trace shown is expected.