The force of contraction can be changed by: can choose more than on e Group of answer choices - muscarinic ACh receptors.  Activation of the receptors leads to decreased Ca2+ entry and increased K+ entry in ventricles.     - Beta2 adrenergic receptors.  Increasing cAMP leads to increases in PKA, which increases sarcoplasmic calcium by opening VG Ca+ channels for a longer time, opening SR Ca2+ channels, and increasing the rate of Ca2+ removed by SERCA pumps.   - Beta1 adrenergic receptors.  Increasing cAMP leads to increases in PKA, which increases sarcoplasmic calcium by opening VG Ca+ channels for a longer time, opening SR Ca2+ channels, and increasing the rate of Ca2+ removed by SERCA pumps.   - Not by the parasympathetic NS. (at least, not the ventricles).

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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The force of contraction can be changed by:
can choose more than on e
Group of answer choices
- muscarinic ACh receptors.  Activation of the receptors leads to decreased Ca2+ entry and increased K+ entry in ventricles.  
 
- Beta2 adrenergic receptors.  Increasing cAMP leads to increases in PKA, which increases sarcoplasmic calcium by opening VG Ca+ channels for a longer time, opening SR Ca2+ channels, and increasing the rate of Ca2+ removed by SERCA pumps.
 
- Beta1 adrenergic receptors.  Increasing cAMP leads to increases in PKA, which increases sarcoplasmic calcium by opening VG Ca+ channels for a longer time, opening SR Ca2+ channels, and increasing the rate of Ca2+ removed by SERCA pumps.
 
- Not by the parasympathetic NS. (at least, not the ventricles).
Expert Solution
Step 1

The force of contraction of heart is referred to as cardiac contractibility. It defines how the heart can generate a force when it is loaded or stretched despite being an independent organ. The force involves the before and after tension and velocity of shortening developed when it is given load. 

 

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