The first step of the lysozyme reaction (catalytic mechanism) is shown in the figure below. Which statement regarding lysozyme is true? Glu 35 HO O(NAM) to (NAG) Asp 52 www a. The local environment of Asp 52 significantly changes its pka. Ob. Glu 35 has an unusually low pKa due to its hydrophobic environment. Oc. Glu 35 provides acid/base assistance during catalysis. Od. Glu 35 acts as a nucleophile during catalysis.
The first step of the lysozyme reaction (catalytic mechanism) is shown in the figure below. Which statement regarding lysozyme is true? Glu 35 HO O(NAM) to (NAG) Asp 52 www a. The local environment of Asp 52 significantly changes its pka. Ob. Glu 35 has an unusually low pKa due to its hydrophobic environment. Oc. Glu 35 provides acid/base assistance during catalysis. Od. Glu 35 acts as a nucleophile during catalysis.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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![The first step of the lysozyme reaction (catalytic mechanism) is shown in the figure below. Which statement regarding lysozyme is true?
Glu 35
HO
O(NAM)
R
(NAG)
Asp 52
a. The local environment of Asp 52 significantly changes its pka.
b. Glu 35 has an unusually low pKa due to its hydrophobic environment.
c. Glu 35 provides acid/base assistance during catalysis.
d. Glu 35 acts as a nucleophile during catalysis.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Ff01b8cd4-7ccd-4d5d-8713-a82b8783858b%2F35e6d22c-8651-4ece-98a9-0591606370e1%2Fox5611u_processed.png&w=3840&q=75)
Transcribed Image Text:The first step of the lysozyme reaction (catalytic mechanism) is shown in the figure below. Which statement regarding lysozyme is true?
Glu 35
HO
O(NAM)
R
(NAG)
Asp 52
a. The local environment of Asp 52 significantly changes its pka.
b. Glu 35 has an unusually low pKa due to its hydrophobic environment.
c. Glu 35 provides acid/base assistance during catalysis.
d. Glu 35 acts as a nucleophile during catalysis.
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