2. Two key amino acid side chains (an Asp and a Glu) essential for lysozyme's catalytic activity are positioned above and below the C₁-0 bond that is cleaved as shown below. Suggest a plausible mechanism for the reaction that starts with a nucleophilic attack at C₁. Glu 35 HO RO-NAG-O RO- ACHN 0 0 но- Asp 52 OH NHAC NAM-OR

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Chapter1: Biochemistry: An Evolving Science
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2. Two key amino acid side chains (an Asp and a Glu) essential for lysozyme's
catalytic activity are positioned above and below the C₁-0 bond that is
cleaved as shown below. Suggest a plausible mechanism for the reaction that
starts with a nucleophilic attack at C₁.
Glu 35
HO
RO-NAG 07
RO
0
دن
1
ACHN
H
HO
Asp 52
OH
NHAC
NAM-OR
NAM-C
Transcribed Image Text:2. Two key amino acid side chains (an Asp and a Glu) essential for lysozyme's catalytic activity are positioned above and below the C₁-0 bond that is cleaved as shown below. Suggest a plausible mechanism for the reaction that starts with a nucleophilic attack at C₁. Glu 35 HO RO-NAG 07 RO 0 دن 1 ACHN H HO Asp 52 OH NHAC NAM-OR NAM-C
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