The doctor orders administration of a drug at 120. mg per 1000. mL at 400 mL /24h. How many mg of drug will the patient receive in 8.0 hours? Show all your calculations.
The doctor orders administration of a drug at 120. mg per 1000. mL at 400 mL /24h. How many mg of drug will the patient receive in 8.0 hours? Show all your calculations.
World of Chemistry, 3rd edition
3rd Edition
ISBN:9781133109655
Author:Steven S. Zumdahl, Susan L. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan L. Zumdahl, Donald J. DeCoste
Chapter2: Matter
Section: Chapter Questions
Problem 22A
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The doctor orders administration of a drug at 120. mg per 1000. mL at 400 mL /24h. How many mg of drug will the patient receive in 8.0 hours? Show all your calculations.
Transcribed Image Text:CHEMICAL CONNECTIONS 1A
Drug Dosage and Body Mass
In many cases, drug dosages are prescribed on the ba-
sis of body mass. For example, the recommended dos-
age of a drug may be 3 mg of drug for each kilogram of
body weight. In this case, a 50 kg (110 lb) woman would
receive 150 mg and an 82 kg (180 lb) man would get
246 mg. This adjustment is especially important
for children, because a dose suitable for an adult will
generally be to0 much for a child, who has much less
body mass. For this reason, manufacturers package and
sell smaller doses of certain drugs, such as aspirin, for
Children's
Dosing Chart
Age (yr)
Dose (tsp)
Weight (Ib)
under 2 yr
ask a doctor
under 24 b
24-35 Ib
2-3 yr
1 tsp
4-5 yr
1 1/2 tsp
36-47 ib
children.
2 tsp
48-59 Ib
6-8 yr
Drug dosage may also vary with age. Occasionally,
when an elderly patient has an impaired kidney or liver
function, the clearance of a drug from the body is de-
layed, and the drug may stay in the body longer than
is normal. This persistence can cause dizziness, vertigo,
and migraine-like headaches, resulting in falls and bro-
ken bones. Such delayed clearance must be monitored
and the drug dosage adjusted accordingly.
9-10 yr
2 1/2 tsp
60-71 Ib
11 yr
3 tsp
72-95 Ib
Grape a Liquid
2-11
This package of Advil has a chart showing
the proper doses for children of a given
weight.
Charles D. Winters
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