The diagram below shows the sites of action for the antibiotics Sulfamethoxazole and Trimethoprim. NOT true? Sulfamethoxazole, a sulfonamide that is a structural analog of PABA, competitively inhibits the synthesis of dihydrofolic acid from PABA 2 Trimethoprim, a structural analog of a portion of dihydrofolic acid, competitively inhibits the synthesis of tetrahydrofolic acid. Creigh O PABA Which of the following statements is Sulfamethoxazole Dihydrofolic acid Trimethoprim Precursors of proteins, DNA, RNA Tetrahydrofolic acid H₂N N H₂N N DNA RNA H₂N OH PABA H NH NH₂ CH₂ C-OH H₂N- SO₂-NHT Sulfamethoxazole O CH, NH Trimethoprim Dihydrofolic acid OCH, -OCH₂ OCH₂ NCH₂ COOH (CH₂)2 NHCH COOH There is synergy between the two antibiotics (less needed in combination than the sum of the two individually) None of the other four answers (All are true statements) Both antibiotics are competitive inhibitors of enzymes that make substances needed by bacteria They have very low differential toxicity because they also inhibit the human folic acid pathway
Musculoskeletal System
The musculoskeletal system, also called the locomotor system, is an organ system that gives humans and animals the ability to move using their muscular and skeletal systems. It provides stability, form, support, and movement to the body. The skeleton is composed of bones (skeleton), muscles, cartilage, tendons, ligaments, joints, and other connective tissue that supports and binds tissues and organs together. The musculoskeletal system is subdivided into two broad systems, such as the muscular system and the skeletal system.
Skeletal structure
The skeletal system is the core framework of the human body. The skeletal structure comprises bones and connective tissue, including cartilage, ligaments, and tendons. The skeletal structure of our body acts as a support structure. It maintains the body's shape and is responsible for its movement, blood cell formation, protection of organs, and mineral storage. The skeletal system is referred to as the musculoskeletal system.
Antibiotics are generally used to kill the microbes by targeting a pathway that is essential for their survival. It is generally used to prevent bacterial infection.
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