The blue sclera allele has 75 percent penetrance for producing blue sclera, 60 percent penetrance for fragile bones, and 40 percent penetrance for deafness. If these probabilities of penetrance are independent, , .percent of individuals with the blue sclera allele will have deafness, blue sclera, and fragile bones. 18 24 45 54 82 O O O O

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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**Question:**
The blue sclera allele has 75 percent penetrance for producing blue sclera, 60 percent penetrance for fragile bones, and 40 percent penetrance for deafness. If these probabilities of penetrance are independent, _______ percent of individuals with the blue sclera allele will have deafness, blue sclera, and fragile bones.

**Options:**
- 18
- 24 (selected answer)
- 45
- 54
- 82

**Explanation:**
To find the percentage of individuals with the blue sclera allele who will have all three traits (deafness, blue sclera, and fragile bones), we need to multiply the probabilities of each individual trait occurring, assuming they are independent of each other.

Given:
- Penetrance for blue sclera = 75% = 0.75
- Penetrance for fragile bones = 60% = 0.60
- Penetrance for deafness = 40% = 0.40

The combined probability is calculated as follows:
\[ \text{Combined probability} = 0.75 \times 0.60 \times 0.40 \]

\[ \text{Combined probability} = 0.75 \times 0.60 = 0.45 \]
\[ \text{Combined probability} = 0.45 \times 0.40 = 0.18 = 18\% \]

The correct answer should thus be 18%. The selected answer, 24, is incorrect as indicated at the bottom of the question.

**Feedback:**
Incorrect
Transcribed Image Text:**Question:** The blue sclera allele has 75 percent penetrance for producing blue sclera, 60 percent penetrance for fragile bones, and 40 percent penetrance for deafness. If these probabilities of penetrance are independent, _______ percent of individuals with the blue sclera allele will have deafness, blue sclera, and fragile bones. **Options:** - 18 - 24 (selected answer) - 45 - 54 - 82 **Explanation:** To find the percentage of individuals with the blue sclera allele who will have all three traits (deafness, blue sclera, and fragile bones), we need to multiply the probabilities of each individual trait occurring, assuming they are independent of each other. Given: - Penetrance for blue sclera = 75% = 0.75 - Penetrance for fragile bones = 60% = 0.60 - Penetrance for deafness = 40% = 0.40 The combined probability is calculated as follows: \[ \text{Combined probability} = 0.75 \times 0.60 \times 0.40 \] \[ \text{Combined probability} = 0.75 \times 0.60 = 0.45 \] \[ \text{Combined probability} = 0.45 \times 0.40 = 0.18 = 18\% \] The correct answer should thus be 18%. The selected answer, 24, is incorrect as indicated at the bottom of the question. **Feedback:** Incorrect
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