The adaptive immune system developed a strategy for monitoring the proteins synthesized in virtually any cell in the body, thereby preventing pathogens from ‘hiding out’ by adopting an intracellular lifestyle. To accomplish this, the immune system: Co-opted the ubiquitin-proteasome system used by cell for protein turnover Created a novel pathway using the immunoproteasome for generating peptides Created a novel pathway to express foreign proteins on the cell surface Took advantage of proteolytic enzymes present in endocytic vesicles
The adaptive immune system developed a strategy for monitoring the proteins synthesized in virtually any cell in the body, thereby preventing pathogens from ‘hiding out’ by adopting an intracellular lifestyle. To accomplish this, the immune system: Co-opted the ubiquitin-proteasome system used by cell for protein turnover Created a novel pathway using the immunoproteasome for generating peptides Created a novel pathway to express foreign proteins on the cell surface Took advantage of proteolytic enzymes present in endocytic vesicles
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter17: Genes And The Immune System
Section: Chapter Questions
Problem 11QP: It is often helpful to draw a complicated pathway in the form of a flow chart to visualize the...
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The adaptive immune system developed a strategy for monitoring the proteins synthesized in virtually any cell in the body, thereby preventing pathogens from ‘hiding out’ by adopting an intracellular lifestyle. To accomplish this, the immune system:
- Co-opted the ubiquitin-proteasome system used by cell for protein turnover
- Created a novel pathway using the immunoproteasome for generating peptides
- Created a novel pathway to express foreign proteins on the cell surface
- Took advantage of proteolytic enzymes present in endocytic vesicles
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