The activity of isocitrate dehydrogenase in E. coli is regulated by the covalent attachment of a phosphate group, which inactivates the enzyme. When acetate is the food source for a culture of E. coli, isocitrate dehydrogenase is phosphorylated. However, when glucose is added to the culture, the phosphate group is removed from isocitrate dehydrogenase. These observations indicate that acetate metabolism proceeds through the citric acid cycle *, while glucose metabolism proceeds through the gluconeogenesis pathway

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Chapter1: Chemical Foundations
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The answer option for the drop down menu are citric acid cycle, gluconeogenesis pathway, and glyoxylate cycle.
The activity of isocitrate dehydrogenase in E. coli is regulated by the covalent attachment of a phosphate group, which inactivates the
enzyme. When acetate is the food source for a culture of E. coli, isocitrate dehydrogenase is phosphorylated. However, when glucose is
added to the culture, the phosphate group is removed from isocitrate dehydrogenase. These observations indicate that acetate
metabolism proceeds through the citric acid cycle
,while glucose metabolism proceeds through the
gluconeogenesis pathway
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Transcribed Image Text:The activity of isocitrate dehydrogenase in E. coli is regulated by the covalent attachment of a phosphate group, which inactivates the enzyme. When acetate is the food source for a culture of E. coli, isocitrate dehydrogenase is phosphorylated. However, when glucose is added to the culture, the phosphate group is removed from isocitrate dehydrogenase. These observations indicate that acetate metabolism proceeds through the citric acid cycle ,while glucose metabolism proceeds through the gluconeogenesis pathway Hint Save for Later Last saved 4 minutes ago. Saved work will be auto-submitted on the due date. Auto-submission can take up to 10 minutes. Attempts: 0 of 2 used Submit Answer
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