Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and two moles of a Grignard reagent, or from a ketone and one mole of a Grignard reagent. Use retrosynthetic analysis to suggest one path of each type to synthesize 2-methyl-2-butanol (or 2-methylbutan-2-ol). он H,0* Reagent 1 + Reagent 2 → Route 1: Select an Ester, , and an appropriate Grignard, to give 2-methyl-2-butanol (or 2-methylbutan-2-ol) after reaction and an aqueous workup. Route 2: Select a ketone, and an appropriate Grignard, to give 2-methyl-2-butanol (or 2-methylbutan-2-ol) after reaction and an aqueous workup.

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Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and two
moles of a Grignard reagent, or from a ketone and one mole of a Grignard reagent. Use retrosynthetic analysis to suggest
one path of each type to synthesize 2-methyl-2-butanol (or 2-methylbutan-2-ol).
OH
H,O*
Reagent 1 + Reagent 2
Route 1: Select an Ester,
and an appropriate Grignard,
, to give
2-methyl-2-butanol (or 2-methylbutan-2-ol) after reaction and an aqueous workup.
Route 2: Select a ketone,
, and an appropriate Grignard,
to give
2-methyl-2-butanol (or 2-methylbutan-2-ol) after reaction and an aqueous workup.
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Transcribed Image Text:Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and two moles of a Grignard reagent, or from a ketone and one mole of a Grignard reagent. Use retrosynthetic analysis to suggest one path of each type to synthesize 2-methyl-2-butanol (or 2-methylbutan-2-ol). OH H,O* Reagent 1 + Reagent 2 Route 1: Select an Ester, and an appropriate Grignard, , to give 2-methyl-2-butanol (or 2-methylbutan-2-ol) after reaction and an aqueous workup. Route 2: Select a ketone, , and an appropriate Grignard, to give 2-methyl-2-butanol (or 2-methylbutan-2-ol) after reaction and an aqueous workup. about us privacy policy terms of use contact us help careers
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