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1,1-diphenylethanol after workup. 2 equiv. CH,CH, MgBr 1 equiv. CH, MgBr 1 equiv. PhMgBr 2 equiv. PhMgBr 1 equiv. CH, CH, MgBr 2 equiv. CH, MgBr

1,1-diphenylethanol after workup. 2 equiv. CH,CH, MgBr 1 equiv. CH, MgBr 1 equiv. PhMgBr 2 equiv. PhMgBr 1 equiv. CH, CH, MgBr 2 equiv. CH, MgBr

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Route 2: Select a ketone, and an appropriate Grignard, to give 1,1-diphenylethanol after workup. 2 equiv. CH, CH, MgBr 1 equiv. CH, MgBr 1 equiv. PhMgBr 2 equiv. PhMgBr 1 equiv. CH, CH, MgBr 2 equiv. CH, MGB.
Transcribed Image Text:Route 2: Select a ketone, and an appropriate Grignard, to give 1,1-diphenylethanol after workup. 2 equiv. CH, CH, MgBr 1 equiv. CH, MgBr 1 equiv. PhMgBr 2 equiv. PhMgBr 1 equiv. CH, CH, MgBr 2 equiv. CH, MGB.
Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and two moles of a Grignard reagent, or from a ketone and one mole of a Grignard reagent. Use retrosynthetic analysis to suggest one path of each type to synthesize 1,1-diphenylethanol. Он H,0* Reagent 1 + Reagent 2 Route 1: Select an Ester, and an appropriate Grignard, , to give 1,1-diphenylethanol after workup. 2 equiv. CH, CH, MgBr Route 2: Select a ketone, d an appropriate Grignard, 1 equiv. CH, MgBr , to give OCH 1,1-diphenylethanol after workup. 2 equiv. PhMgBr 1 equiv. CH,CH, MgBr OCH 2 equiv. CH, MgBr 1 equiv. PhMgBr OCH3
Transcribed Image Text:Tertiary alcohols with two identical alkyl groups attached to the alcohol carbon can be made either from an ester and two moles of a Grignard reagent, or from a ketone and one mole of a Grignard reagent. Use retrosynthetic analysis to suggest one path of each type to synthesize 1,1-diphenylethanol. Он H,0* Reagent 1 + Reagent 2 Route 1: Select an Ester, and an appropriate Grignard, , to give 1,1-diphenylethanol after workup. 2 equiv. CH, CH, MgBr Route 2: Select a ketone, d an appropriate Grignard, 1 equiv. CH, MgBr , to give OCH 1,1-diphenylethanol after workup. 2 equiv. PhMgBr 1 equiv. CH,CH, MgBr OCH 2 equiv. CH, MgBr 1 equiv. PhMgBr OCH3
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