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Terminators The addition of an excess of ddNTP leads to the stop of DNA replication in bacteria: explain the biochemistry behind this process (hint: the chemical structures of NTP, DNTP and ddNTP are shown below). "o- "o-P-o "o-P-o "o-p-o "o-p-o "o-P-o "o-P-o "o--o Base Base Base CH, CH, CH, H. H. H H. H. он он OH H Ribonucleoside triphosphate NTP) Deoxyribonucleoside triphosphate (dNTP) Dideoxyribonucleoside triphosphate iddNTP)

Terminators The addition of an excess of ddNTP leads to the stop of DNA replication in bacteria: explain the biochemistry behind this process (hint: the chemical structures of NTP, DNTP and ddNTP are shown below). "o- "o-P-o "o-P-o "o-p-o "o-p-o "o-P-o "o-P-o "o--o Base Base Base CH, CH, CH, H. H. H H. H. он он OH H Ribonucleoside triphosphate NTP) Deoxyribonucleoside triphosphate (dNTP) Dideoxyribonucleoside triphosphate iddNTP)

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Terminators The addition of an excess of ddNTP leads to the stop of DNA replication in bacteria: explain the biochemistry behind this process (hint: the chemical structures of NTP, DNTP and ddNTP are shown below). "o-P-o "0-P-o "o-P-o "o-P-o "O-P-o "o-P-o "0-P-o "o-P-o -o-P-o Base Base Base CH, CH, CH, H. H. OH OH ÓH H Dideoxyribonucleoside triphosphate (ddNTP) Ribonucleoside triphosphate (NTP) Deoxyribonucleoside triphosphate (DNTP)
Transcribed Image Text:Terminators The addition of an excess of ddNTP leads to the stop of DNA replication in bacteria: explain the biochemistry behind this process (hint: the chemical structures of NTP, DNTP and ddNTP are shown below). "o-P-o "0-P-o "o-P-o "o-P-o "O-P-o "o-P-o "0-P-o "o-P-o -o-P-o Base Base Base CH, CH, CH, H. H. OH OH ÓH H Dideoxyribonucleoside triphosphate (ddNTP) Ribonucleoside triphosphate (NTP) Deoxyribonucleoside triphosphate (DNTP)
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