te the structure for a generic triacylglyceride at pH 7.4.
Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter6: Basic Clinical Chemistry
Section6.6: Blood Cholesterol And Triglycerides
Problem 4CS
Related questions
Question
![22) A) Write the structure for a generic triacvlglyceride at pH 7.4. B) Show the mechanism
of a lipase including the catalytic triad and the oxyanion hole up to the tetrahedral
intermediate of the cleavage of the acyl-alcohol bond. C) What is the purpose of the
þxyanion hole? D) How does the catalytic triad function to lower the pKa of serine.
coo
coo
H,N-C-H
H,N-C-H
CH,
CH2
он
Serine (S)
(Ser)
HN
Histidine (H)
(His)
coo
co
H,N-C-H
H,N-C-H
H
CH,
Glycine (G)
(Gly)
coo
Aspartate [D]
(Asp)](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F4f6ffd6a-7f27-4efb-8c32-bf353625c5ae%2Fbef8cf09-7a00-4fb7-84f9-8e48476d8164%2F8kgsztf_processed.jpeg&w=3840&q=75)
Transcribed Image Text:22) A) Write the structure for a generic triacvlglyceride at pH 7.4. B) Show the mechanism
of a lipase including the catalytic triad and the oxyanion hole up to the tetrahedral
intermediate of the cleavage of the acyl-alcohol bond. C) What is the purpose of the
þxyanion hole? D) How does the catalytic triad function to lower the pKa of serine.
coo
coo
H,N-C-H
H,N-C-H
CH,
CH2
он
Serine (S)
(Ser)
HN
Histidine (H)
(His)
coo
co
H,N-C-H
H,N-C-H
H
CH,
Glycine (G)
(Gly)
coo
Aspartate [D]
(Asp)
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
Step by step
Solved in 2 steps with 2 images
Recommended textbooks for you
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Human Heredity: Principles and Issues (MindTap Co…
Biology
ISBN:
9781305251052
Author:
Michael Cummings
Publisher:
Cengage Learning
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Human Heredity: Principles and Issues (MindTap Co…
Biology
ISBN:
9781305251052
Author:
Michael Cummings
Publisher:
Cengage Learning
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Anatomy & Physiology
Biology
ISBN:
9781938168130
Author:
Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher:
OpenStax College