Tay-Sachs disease is a recessive genetic disease. Individuals with this disease rarely survive past the age of four. In the general population, approximately 1 person in 300 carries the allele for this disease. However, in some populations, including the Irish Americans, the Ashkenazi Jews and the Cajuns from Louisiana, the proportion of Tay-Sachs carriers is much higher (1 in 27 to 1 in 50) than in other populations. Which evolutionary scenario can be predicted to produce a high frequency of Tay-Sachs disease in these populations?

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Health Epidemiology

Health is an essential factor for all human beings. For all humans, health is a critical factor. An individual's ability to meet life's challenges and retain his or her capacity for optimal functioning is reflected in his or her condition of health. This needs the physical, mental, and biological parts of one's constitution to maintain a degree of functioning that has a favorable influence and support for one another.