Tablet powder containing 80 mg of promazine hydrochloride is ground to a paste with 10 ml of 2 M HCl. The paste is then diluted with 200 ml of water, shaken for 15 min and finally made up to 500 ml. A portion of the extract is filtered. Then, 5 ml of the filtrate is taken and diluted to 120 ml with 0.1 M HCl. – Absorbance reading=0.755 is read at a wavelength wavelength of 251 nm – A (1%, 1 cm) value of promazine.HCl at 251 nm=935 – Stated content of promazine.HCl per tablet=50 mg – Weight of 20 tablets=1.667 g – Weight of tablet powder taken for assay=163 mg expected content in tablet taken is: A-97.78 g/mL B-97.78 g/100ml C-0.0097g/mL D-97.78 mg/100ml Concentration in diluted tablet extract is: A-0.81g/mL B-80 g/100ml C-0.00081g/mL D-0.807 mg/100ml Concentration in original tablet extract is: A-19.38g/mL B-16.15 mg/100ml C-19.38 mg/100ml D-16.15 mg/mL Amount of promazine.HCl in original extract is: A-96.90mg B-80.75mg C-96.90mg/100ml D-80.75mg/100ml percentage of stated content is: A-99.1 mg B-80.75mg C-99.1 mg/100ml D-80.75mg/100ml
Tablet powder containing 80 mg of promazine hydrochloride is ground to a paste with 10 ml of 2 M HCl. The paste is then diluted with 200 ml of water, shaken for 15 min and finally made up to 500 ml. A portion of the extract is filtered. Then, 5 ml of the filtrate is taken and diluted to 120 ml with 0.1 M HCl. – Absorbance reading=0.755 is read at a wavelength wavelength of 251 nm – A (1%, 1 cm) value of promazine.HCl at 251 nm=935 – Stated content of promazine.HCl per tablet=50 mg – Weight of 20 tablets=1.667 g – Weight of tablet powder taken for assay=163 mg expected content in tablet taken is: A-97.78 g/mL B-97.78 g/100ml C-0.0097g/mL D-97.78 mg/100ml Concentration in diluted tablet extract is: A-0.81g/mL B-80 g/100ml C-0.00081g/mL D-0.807 mg/100ml Concentration in original tablet extract is: A-19.38g/mL B-16.15 mg/100ml C-19.38 mg/100ml D-16.15 mg/mL Amount of promazine.HCl in original extract is: A-96.90mg B-80.75mg C-96.90mg/100ml D-80.75mg/100ml percentage of stated content is: A-99.1 mg B-80.75mg C-99.1 mg/100ml D-80.75mg/100ml
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Tablet powder containing 80 mg of promazine hydrochloride is ground to a paste with 10 ml of 2 M HCl. The paste is then diluted with 200 ml of water, shaken for 15 min and finally made up to 500 ml. A portion of the extract is filtered. Then, 5 ml of the filtrate is taken and diluted to 120 ml with 0.1 M HCl.
– Absorbance reading=0.755 is read at a wavelength wavelength of 251 nm
– A (1%, 1 cm) value of promazine.HCl at 251 nm=935
– Stated content of promazine.HCl per tablet=50 mg
– Weight of 20 tablets=1.667 g
– Weight of tablet powder taken for assay=163 mg
expected content in tablet taken is:
A-97.78 g/mL
B-97.78 g/100ml
C-0.0097g/mL
D-97.78 mg/100ml
Concentration in diluted tablet extract is:
A-0.81g/mL
B-80 g/100ml
C-0.00081g/mL
D-0.807 mg/100ml
Concentration in original tablet extract is:
A-19.38g/mL
B-16.15 mg/100ml
C-19.38 mg/100ml
D-16.15 mg/mL
Amount of promazine.HCl in original extract is:
A-96.90mg
B-80.75mg
C-96.90mg/100ml
D-80.75mg/100ml
percentage of stated content is:
A-99.1 mg
B-80.75mg
C-99.1 mg/100ml
D-80.75mg/100ml
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