Table 4.18 shows estimated effects for a fitted logistic regression model with squamous cell esophageal cancer (1 = yes, 0 = no) as the response variable Y. Smoking status (S) equals 1 for at least one pack per day and 0 other- wise, alcohol consumption (A) equals the average number of alcoholic drinks consumed per day, and race (R) equals 1 for blacks and 0 for whites. A. To describe the race-by-smoking interaction, construct the prediction equation when R = 1 and again when R = 0. Find the fitted YS conditional odds ratio for each case. Similarly, construct the prediction equation when S = 1 and again when S = 0. Find the fitted YR conditional odds ratio for each case. Note that, for each association, the coefficient of the cross-product term is the difference between the log odds ratios at the two fixed levels for the other variable. B. In Table 4.18, explain what the coefficients of R and S represent, for the coding as given above. What hypotheses do the P -values refer to for these variables? C. Suppose the model also contained an A × R interaction term, with coefficient 0.04. In the prediction equation, show that this represents the difference between the effect of A for blacks and for whites.

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Table 4.18 shows estimated effects for a fitted logistic regression model with squamous cell esophageal cancer (1 = yes, 0 = no) as the response variable Y. Smoking status (S) equals 1 for at least one pack per day and 0 other- wise, alcohol consumption (A) equals the average number of alcoholic drinks consumed per day, and race (R) equals 1 for blacks and 0 for whites. A. To describe the race-by-smoking interaction, construct the prediction equation when R = 1 and again when R = 0. Find the fitted YS conditional odds ratio for each case. Similarly, construct the prediction equation when S = 1 and again when S = 0. Find the fitted YR conditional odds ratio for each case. Note that, for each association, the coefficient of the cross-product term is the difference between the log odds ratios at the two fixed levels for the other variable. B. In Table 4.18, explain what the coefficients of R and S represent, for the coding as given above. What hypotheses do the P -values refer to for these variables? C. Suppose the model also contained an A × R interaction term, with coefficient 0.04. In the prediction equation, show that this represents the difference between the effect of A for blacks and for whites.
Table 4.18. Table for Problem 4.23 on Effects on
Esophageal Cancer
Variable
Intercept
Alcohol use
Smoking
Race
Race x smoking
Effect
-7.00
0.10
1.20
0.30
0.20
P-value
<0.01
0.03
<0.01
0.02
0.04
Transcribed Image Text:Table 4.18. Table for Problem 4.23 on Effects on Esophageal Cancer Variable Intercept Alcohol use Smoking Race Race x smoking Effect -7.00 0.10 1.20 0.30 0.20 P-value <0.01 0.03 <0.01 0.02 0.04
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