I just want to double check my answers are in bold for both questions thank you!Supercoiling of pure circular DNA is a result of ________. A.underwinding or overwinding of the helix B.entanglements because of the long length of the strands C.the lack of associated histones D.the activity of exonucleases It is easier to melt DNA richer in AT than GC because A.it is more heat sensitive. B.there is one less hydrogen bond in an AT base pair. C. the helix pitch is longer in AT rich regions. D.All of the above

DNA is the nucleic acid present as the genetic material in most of the organisms. DNA is the deoxy-ribo nucleic acid in which deoxyribose sugar molecules are attached with nitrogenous bases and phosphate groups. DNA is transcribed into messenger RNA and this mRNA undergoes translation into proteins. Supercoiling of pure circular DNA is a result of underwinding or overwinding of the helix. This is true. This happens when the two DNA strands are unwinded during replication by breaking their hydrogen bonds in between and each strand becomes overwinded by the tension in the coil. This is repaired by topoisomerases. It is easier to melt DNA richer in AT than GC because there is one less hydrogen bond in an AT base pair. This is true. The GC bond has triple H-bonds whereas AT has double H-bonds.

Answered: Supercoiling of pure circular DNA is a…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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I just want to double check my answers are in bold for both questions
thank you!

Supercoiling of pure circular DNA is a result of ________.

	A.	underwinding or overwinding of the helix
	B.	entanglements because of the long length of the strands
	C.	the lack of associated histones
	D.	the activity of exonucleases

It is easier to melt DNA richer in AT than GC because

	A.	it is more heat sensitive.
	B.	there is one less hydrogen bond in an AT base pair.
	C.	the helix pitch is longer in AT rich regions.
	D.	All of the above

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