Skin cancer requires a number of mutations, several of which are often caused by the sun in individual skin cells. With this is mind, if you develop melanoma (skin cancer) on your arm, will you pass on that same melanoma to your offspring? Why or why not? Explain in your own words.
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- Skin cancer requires a number of mutations, several of which are often caused by the sun in individual skin cells. With this is mind, if you develop melanoma (skin cancer) on your arm, will you pass on that same melanoma to your offspring? Why or why not? Explain in your own words.
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- Why is it only the risk for cancer that is inherited?Hair color is due to the presence of melanin. There are two types of melanin produced by melanocytes. One is eumelanin, which is responsible for black (homozygous), brown (heterozygous), and blond (recessive) hair colors. The other is pheomelanin, which is responsible for red hair color. During melanin synthesis, MCR1gene converts pheomelanin to eumelanin. However, a variant of the MCR1 gene (MCR1variant), prevents this conversion. A cross between a blond-haired mother and a red-haired father produced 100% brown-haired children. When they came of age, one child married a double heterozygote, and both were blessed with 7 children; 2 with black hair, 2 with brown hair, 1 with blond hair, and 2 with red hair. TIP: Black hair is homozygous while brown hair is heterozygous, thus represented together in determining the ratio and written as black/brown in the 9:3:3:1 ratio. However, all F2s must be given their COMPLETE genotypes. Using the 7-step method, determine the genotypes of the…A carcinogenic compound is placed on the skin of inbred laboratory mice. In many of these mice, skin tumors develop at the site of exposure, but only monthsafter the chemical is no longer detectable. Why don’tall the mice develop tumors, and why don’t the tumorsappear much sooner?
- The first three center around extranuclear inheritance involving DNA in organelles. The fourth involves what is called maternal effect. Write a short essay that distinguishes between organelle heredity and maternal effect.A 14-year-old girl has some abnormalities: her height is lower than that of the girls of the same age, the signs of puberty are absent, her neck is very short, her shoulders are wide. During the cytogenetic analysis the lack of one X-chromosome was found. The girl has normal intellectual development. What disease does the girl have? Select one: a. Turner's syndrome. b. Down's syndrome. c. Edward's syndrome. d. Patau syndrome. O e. Klinefelter's syndrome.Why is the Philadelphia chromosome important to understanding & treating some cancers, especially CML?
- Is it correct to say that the palladin gene causes cancer?Most forms of cancer are caused by environmental agents that produce mutations in somatic cells. Is an individual with cancer considered a genetic mosaic? Explain why or why not.Retinoblastoma is a rare cancer in which tumors developin the retina of the eye. The tumors arise because of theloss of the Rb gene, which codes for a tumor suppressor.Hereditary retinoblastoma usually appears in children whohave inherited only one functional copy of Rb. Explain whythe nonhereditary form of retinoblastoma usually occurs laterin life.
- Breast cancer is one of the most common cancers among women. The exact cause of breast cancer is unknown, and very few women will know the reason why they got it. We do know that breast cancer is always caused by damage to DNA. When the cell’s DNA is damaged, mutated cells begin to grow uncontrollably. These abnormal cells can progress into a disease such as breast cancer. Women with certain risk factors are more likely to get breast cancer than others. Some risk factors caused by the environment can be avoided, while others, such as family history, cannot. Below are three different women’s stories and their history in relation to breast cancer. Read each scenario and familiarize yourself with each one. For additional background, you can refer to the following website: http://www.nationalbreastcancer.org. Scenario 1: Jennifer is a 40-year-old Caucasian woman who has a history of breast cancer in her family. Her grandmother and mom both had breast cancer. This prompted Jennifer to have…Henry is adopted. He has hair on the back of his hand. Could both of his parents have had no hair on the back of their hand? Explain.One of your patients, a six-year-old girl who suffers from Sickle cell anemia, an inherited blood disorder in which red blood cells are abnormally shaped and fragile, leading to a short supply of red blood cells. These abnormal cells can also get stuck in small vessels, which prevent blood flow, leading to fatigue, pain and other severe complications. If your patient's parents decide to have another child, what is the chance that that child will also have sickle cell anemia? 0% 25% 50% 75% 100%