Sickle cell hemoglobin DNA CACG T AGACTGAGGA CAC Sickle cell hemoglobin MRNA ickle cell hemoglobin AA sequence ValoHis.ku thro pro . Glu What type of mutation is this? Please explain why.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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What type of mutation is this?
1.
Which type of mutation is responsible for new varia tions of a trait?
Which type of mutation does not result in an abnormal amino acid sequece?
Which type of mutation stops the translation of an mRNA molecule?
2.
Sickle Cell Anemia
Sickle cell anemia is the result of a type of mutation in the gene that codes for part of the hemoglobin molecule
Hemoglobin carries oxygen in your red bloods cells. The mutation causes these red blood cells to become stife
sickle-shaped when they release their oxygen. The sickled cells tend to get stuck in blood vessels, causing poin ond
increased risk of stroke, blindness, damage to the heart & lungs, and other conditions.
Analyze the DNA strands below to determine what amino acid is changed AND what type of mutation occurred
Normal hemoglobin DNA
A
G
TC
Normal hemoglobin mRNA
val• Hisolelo thr•proo Gll
Normal hemoglobin AA sequence
CA cGT AG A CTGAGG AC AC
Sickle cell hemoglobin DNA
Sickle cell hemoglobin mRNA
Sickle cell hemoglobin AA sequence ValoHis eu thiro pro . GlU
What type of mutation is this? Please explain why.
Transcribed Image Text:What type of mutation is this? 1. Which type of mutation is responsible for new varia tions of a trait? Which type of mutation does not result in an abnormal amino acid sequece? Which type of mutation stops the translation of an mRNA molecule? 2. Sickle Cell Anemia Sickle cell anemia is the result of a type of mutation in the gene that codes for part of the hemoglobin molecule Hemoglobin carries oxygen in your red bloods cells. The mutation causes these red blood cells to become stife sickle-shaped when they release their oxygen. The sickled cells tend to get stuck in blood vessels, causing poin ond increased risk of stroke, blindness, damage to the heart & lungs, and other conditions. Analyze the DNA strands below to determine what amino acid is changed AND what type of mutation occurred Normal hemoglobin DNA A G TC Normal hemoglobin mRNA val• Hisolelo thr•proo Gll Normal hemoglobin AA sequence CA cGT AG A CTGAGG AC AC Sickle cell hemoglobin DNA Sickle cell hemoglobin mRNA Sickle cell hemoglobin AA sequence ValoHis eu thiro pro . GlU What type of mutation is this? Please explain why.
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