Shown are results of clinical FACS analysis of a normal individual and a patient with X-linked agammaglobulinemia (XLA). Blood lymphocytes from these two patients were incubated with antibodies that recognize the B-cell marker CD19 and the T-cell marker CD3 and then sorted by flow cytometry. Which patient is healthy? Please select.
Shown are results of clinical FACS analysis of a normal individual and a patient with X-linked agammaglobulinemia (XLA). Blood lymphocytes from these two patients were incubated with antibodies that recognize the B-cell marker CD19 and the T-cell marker CD3 and then sorted by flow cytometry. Which patient is healthy? Please select.
Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
Section: Chapter Questions
Problem 1SRQ
Related questions
Question
Transcribed Image Text:Shown are results of clinical FACS analysis of a normal individual and a patient with X-linked
agammaglobulinemia (XLA). Blood lymphocytes from these two patients were incubated with
antibodies that recognize the B-cell marker CD19 and the T-cell marker CD3 and then sorted by flow
cytometry. Which patient is healthy? Please select.
CD3
CD3
O Patient on the right is healthy and patient on the left has a disease. Blood lymphocytes from an individual on
the left show only binding to antibodies against the T-cell marker CD3. This indicates an absence of B cells in
this patient.
Both patients are ill because they do not have cells that are positive for both the CD3 and CD19 markers.
O Patient on the left is healthy and patient on the right has a disease. Blood lymphocytes from an individual on
the left show a large number of T-cells with CD3 marker and a lower concentration of B-cells, which is normal.
CD19
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 2 steps
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, nursing and related others by exploring similar questions and additional content below.Recommended textbooks for you
Phlebotomy Essentials
Nursing
ISBN:
9781451194524
Author:
Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:
JONES+BARTLETT PUBLISHERS, INC.
Gould's Pathophysiology for the Health Profession…
Nursing
ISBN:
9780323414425
Author:
Robert J Hubert BS
Publisher:
Saunders
Fundamentals Of Nursing
Nursing
ISBN:
9781496362179
Author:
Taylor, Carol (carol R.), LYNN, Pamela (pamela Barbara), Bartlett, Jennifer L.
Publisher:
Wolters Kluwer,
Phlebotomy Essentials
Nursing
ISBN:
9781451194524
Author:
Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:
JONES+BARTLETT PUBLISHERS, INC.
Gould's Pathophysiology for the Health Profession…
Nursing
ISBN:
9780323414425
Author:
Robert J Hubert BS
Publisher:
Saunders
Fundamentals Of Nursing
Nursing
ISBN:
9781496362179
Author:
Taylor, Carol (carol R.), LYNN, Pamela (pamela Barbara), Bartlett, Jennifer L.
Publisher:
Wolters Kluwer,
Fundamentals of Nursing, 9e
Nursing
ISBN:
9780323327404
Author:
Patricia A. Potter RN MSN PhD FAAN, Anne Griffin Perry RN EdD FAAN, Patricia Stockert RN BSN MS PhD, Amy Hall RN BSN MS PhD CNE
Publisher:
Elsevier Science
Study Guide for Gould's Pathophysiology for the H…
Nursing
ISBN:
9780323414142
Author:
Hubert BS, Robert J; VanMeter PhD, Karin C.
Publisher:
Saunders
Issues and Ethics in the Helping Professions (Min…
Nursing
ISBN:
9781337406291
Author:
Gerald Corey, Marianne Schneider Corey, Cindy Corey
Publisher:
Cengage Learning